Fabrication of highly uniform gel coatings by the conversion of surface-anchored metal-organic frameworks

Manuel Tsotsalas; Jinxuan Liu; Beatrix Tettmann; Sylvain Grosjean; Artak Shahnas; Zhengbang Wang; Carlos Azucena; Matthew Addicoat; Thomas Heine; Joerg Lahann; Jörg Overhage; Stefan Bräse; Hartmut Gliemann; Christof Wöll

doi:10.1021/ja409205s

Fabrication of highly uniform gel coatings by the conversion of surface-anchored metal-organic frameworks

Manuel Tsotsalas, Jinxuan Liu, Beatrix Tettmann, Sylvain Grosjean, Artak Shahnas, Zhengbang Wang, Carlos Azucena, Matthew Addicoat, Thomas Heine, Joerg Lahann, Jörg Overhage, Stefan Bräse, Hartmut Gliemann, Christof Wöll

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

65 Citations (Scopus)

Abstract

We report the fabrication of 3D, highly porous, covalently bound polymer films of homogeneous thickness. These surface-bound gels combine the advantages of metal-organic framework (MOF) materials, namely, the enormous flexibility and the large size of the maximum pore structures and, in particular, the possibility to grow them epitaxially on modified substrates, with those of covalently connected gel materials, namely, the absence of metal ions in the deposited material, a robust framework consisting of covalent bonds, and, most importantly, pronounced stability under biological conditions. The conversion of a SURMOF (surface-mounted MOF) yields a surface-grafted gel. These SURGELs can be loaded with bioactive compounds and applied as bioactive coatings and provide a drug-release platform in in vitro cell culture studies.

Original language	English
Pages (from-to)	8-11
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	136
Issue number	1
DOIs	https://doi.org/10.1021/ja409205s
Publication status	Published - 2014 Jan 8

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja409205s

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Tsotsalas, M., Liu, J., Tettmann, B., Grosjean, S., Shahnas, A., Wang, Z., Azucena, C., Addicoat, M., Heine, T., Lahann, J., Overhage, J., Bräse, S., Gliemann, H., & Wöll, C. (2014). Fabrication of highly uniform gel coatings by the conversion of surface-anchored metal-organic frameworks. Journal of the American Chemical Society, 136(1), 8-11. https://doi.org/10.1021/ja409205s

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abstract = "We report the fabrication of 3D, highly porous, covalently bound polymer films of homogeneous thickness. These surface-bound gels combine the advantages of metal-organic framework (MOF) materials, namely, the enormous flexibility and the large size of the maximum pore structures and, in particular, the possibility to grow them epitaxially on modified substrates, with those of covalently connected gel materials, namely, the absence of metal ions in the deposited material, a robust framework consisting of covalent bonds, and, most importantly, pronounced stability under biological conditions. The conversion of a SURMOF (surface-mounted MOF) yields a surface-grafted gel. These SURGELs can be loaded with bioactive compounds and applied as bioactive coatings and provide a drug-release platform in in vitro cell culture studies.",

author = "Manuel Tsotsalas and Jinxuan Liu and Beatrix Tettmann and Sylvain Grosjean and Artak Shahnas and Zhengbang Wang and Carlos Azucena and Matthew Addicoat and Thomas Heine and Joerg Lahann and J{\"o}rg Overhage and Stefan Br{\"a}se and Hartmut Gliemann and Christof W{\"o}ll",

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Tsotsalas, M, Liu, J, Tettmann, B, Grosjean, S, Shahnas, A, Wang, Z, Azucena, C, Addicoat, M, Heine, T, Lahann, J, Overhage, J, Bräse, S, Gliemann, H & Wöll, C 2014, 'Fabrication of highly uniform gel coatings by the conversion of surface-anchored metal-organic frameworks', Journal of the American Chemical Society, vol. 136, no. 1, pp. 8-11. https://doi.org/10.1021/ja409205s

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AU - Tsotsalas, Manuel

AU - Liu, Jinxuan

AU - Tettmann, Beatrix

AU - Grosjean, Sylvain

AU - Shahnas, Artak

AU - Wang, Zhengbang

AU - Azucena, Carlos

AU - Addicoat, Matthew

AU - Heine, Thomas

AU - Lahann, Joerg

AU - Overhage, Jörg

AU - Bräse, Stefan

AU - Gliemann, Hartmut

AU - Wöll, Christof

PY - 2014/1/8

Y1 - 2014/1/8

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AB - We report the fabrication of 3D, highly porous, covalently bound polymer films of homogeneous thickness. These surface-bound gels combine the advantages of metal-organic framework (MOF) materials, namely, the enormous flexibility and the large size of the maximum pore structures and, in particular, the possibility to grow them epitaxially on modified substrates, with those of covalently connected gel materials, namely, the absence of metal ions in the deposited material, a robust framework consisting of covalent bonds, and, most importantly, pronounced stability under biological conditions. The conversion of a SURMOF (surface-mounted MOF) yields a surface-grafted gel. These SURGELs can be loaded with bioactive compounds and applied as bioactive coatings and provide a drug-release platform in in vitro cell culture studies.

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Fabrication of highly uniform gel coatings by the conversion of surface-anchored metal-organic frameworks

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