Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

Sungjin Park; Injae Shin

doi:10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S

Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

Sungjin Park, Injae Shin

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

244 Citations (Scopus)

Abstract

A new tool for the high-throughput study of carbohydrate-protein interactions: Maleimide-linked carbohydrates (e.g. 1) were immobilized on thiol-derivatized glass slides, and the microspots were probed with fluorescein-labeled lectins (see picture). The binding of lectins to the carbohydrates on the slide depends on the concentration of the immobilized carbohydrates and on the length of the tethers.

Original language	English
Pages (from-to)	3180-3182
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	41
Issue number	17
DOIs	https://doi.org/10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S
Publication status	Published - 2002 Sept 2

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/1521-3773(20020902)41:17<3180::AID-ANIE3180>3.0.CO;2-S

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Fabrication of carbohydrate chips for studying protein-carbohydrate interactions

Abstract

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