A super-resolved axial imaging technique was investigated based on extraordinary transmission (EOT) of light using metallic gradient nanoaperture arrays. Light through subwavelength nanoapertures at thick metal film can be transmitted and amplified by several orders of magnitude due to plasmonic coupling. Here, the feasibility of EOT-based axial imaging with super resolution is explored. Since light penetration of EOT is much deeper than that of evanescent waves, the axial range to obtain the distance information of fluorescence signals can be extended by EOT. The axial distribution of ganglioside in mouse macrophage cells was measured with sub-diffraction-limited resolution after reconstruction using differential fluorescence excitation on gradient aperture arrays.
|Title of host publication||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XII|
|Editors||Dan V. Nicolau, Alexander N. Cartwright|
|Publication status||Published - 2015|
|Event||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XII - San Francisco, United States|
Duration: 2015 Feb 9 → 2015 Feb 12
|Name||Progress in Biomedical Optics and Imaging - Proceedings of SPIE|
|Other||Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XII|
|Period||15/2/9 → 15/2/12|
Bibliographical notePublisher Copyright:
© 2015 SPIE.
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging