Extraction of microcystins from cyanobacteria by acetic-acid modified supercritical CO2

Dongjin Pyo, Keunyoung Park, Hyundu Shin, Myeonghee Moon

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


A new method for the fast extraction of microcystins RR and LR in cyanobacterium was developed using supercritical CO2. The microcystins were successfully extracted with a ternary mixture (90 % CO2, 9.5 % acetic acid. 0.5 % water). The method developed here has several advantages over solid- phase extraction sample preparation for the analysis of microcystins. Sample handling steps are minimized, thus reducing possible losses of analytes and saving analysis time. No organic solvent extractions are involved in this method and no clean-up steps are employed.

Original languageEnglish
Pages (from-to)539-542
Number of pages4
Issue number9-10
Publication statusPublished - 1999

Bibliographical note

Funding Information:
This investigation was supported by a grant from Korea Science and Engineering foundation (KOSEF, 97-0501-07-01-3). This work was also supported partially by the Ministry of Education (BSRI-97-3425).

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry
  • Organic Chemistry


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