Exploring esophageal microbiomes in esophageal diseases: A systematic review

Chan Hyuk Park, Sang Kil Lee

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)


Studies that investigated esophageal microbiomes are limited when compared to those on intestinal microbiomes. Nevertheless, several studies have investigated the relationship between esophageal microbiomes and various esophageal diseases, owing to the advancement of next-generation sequencing techniques. Streptococcus is the most common bacterial taxon in a normal esophagus. Additionally, Haemophilus, Neisseria, Prevotella, and Veillonella are also found. However, gram-negative bacteria, including Prevotella, are more abundant in a diseased esophagus, such as in gastroesophageal reflux disease and Barrett's esophagus. This systematic review aims to summarize current evidences on esophageal microbiomes in various esophageal diseases.

Original languageEnglish
Pages (from-to)171-179
Number of pages9
JournalJournal of Neurogastroenterology and Motility
Issue number2
Publication statusPublished - 2020 Apr 1

Bibliographical note

Publisher Copyright:
© 2020 The Korean Society of Neurogastroenterology and Motility

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Gastroenterology


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