TY - JOUR
T1 - Expert consensus document
T2 - Semantics in active surveillance for men with localized prostate cancer-results of a modified Delphi consensus procedure
AU - Movember Foundation's Global Action Plan Prostate Cancer Active Surveillance (GAP3) consortium
AU - Bruinsma, Sophie M.
AU - Roobol, Monique J.
AU - Carroll, Peter R.
AU - Klotz, Laurence
AU - Pickles, Tom
AU - Moore, Caroline M.
AU - Gnanapragasam, Vincent J.
AU - Villers, Arnauld
AU - Rannikko, Antti
AU - Valdagni, Riccardo
AU - Frydenberg, Mark
AU - Kakehi, Yoshiyuki
AU - Filson, Christopher P.
AU - Bangma, Chris H.
AU - Trock, B.
AU - Ehdaie, B.
AU - Kim, J.
AU - Morgan, T.
AU - Hyndman, E.
AU - Van Hemelrijck, M.
AU - Dasgupta, P.
AU - Perry, A.
AU - Hugosson, J.
AU - Rubio-Briones, J.
AU - Bjartell, A.
AU - Hefermehl, L.
AU - Lui Shiong, L.
AU - Ha Chung, B.
AU - Suk Lee, K.
AU - van der Kwast, T.
AU - Obbink, H.
AU - van der Linden, W.
AU - Hulsen, Tim
AU - de Jonge, C.
AU - Kattan, M.
AU - Xinge, J.
AU - Muir, K.
AU - Lophatananon, A.
AU - Fahey, M.
AU - Steyerberg, E.
AU - Nieboer, D.
AU - Zhang, L.
AU - Guo, W.
AU - Milan, T.
AU - Benfante, N.
AU - Cowan, J.
AU - Patil, D.
AU - Sanford, R.
AU - Kim, T. K.
AU - Mamedov, A.
N1 - Publisher Copyright:
© 2017 Macmillan Publishers Limited, part of Springer Nature. All rights reserved.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Active surveillance (AS) is broadly described as a management option for men with low-risk prostate cancer, but semantic heterogeneity exists in both the literature and in guidelines. To address this issue, a panel of leading prostate cancer specialists in the field of AS participated in a consensus-forming project using a modified Delphi method to reach international consensus on definitions of terms related to this management option. An iterative three-round sequence of online questionnaires designed to address 61 individual items was completed by each panel member. Consensus was considered to be reached if ≥70% of the experts agreed on a definition. To facilitate a common understanding among all experts involved and resolve potential ambiguities, a face-to-face consensus meeting was held between Delphi survey rounds two and three. Convenience sampling was used to construct the panel of experts. In total, 12 experts from Australia, France, Finland, Italy, the Netherlands, Japan, the UK, Canada and the USA participated. By the end of the Delphi process, formal consensus was achieved for 100% (n = 61) of the terms and a glossary was then developed. Agreement between international experts has been reached on relevant terms and subsequent definitions regarding AS for patients with localized prostate cancer. This standard terminology could support multidisciplinary communication, reduce the extent of variations in clinical practice and optimize clinical decision making.
AB - Active surveillance (AS) is broadly described as a management option for men with low-risk prostate cancer, but semantic heterogeneity exists in both the literature and in guidelines. To address this issue, a panel of leading prostate cancer specialists in the field of AS participated in a consensus-forming project using a modified Delphi method to reach international consensus on definitions of terms related to this management option. An iterative three-round sequence of online questionnaires designed to address 61 individual items was completed by each panel member. Consensus was considered to be reached if ≥70% of the experts agreed on a definition. To facilitate a common understanding among all experts involved and resolve potential ambiguities, a face-to-face consensus meeting was held between Delphi survey rounds two and three. Convenience sampling was used to construct the panel of experts. In total, 12 experts from Australia, France, Finland, Italy, the Netherlands, Japan, the UK, Canada and the USA participated. By the end of the Delphi process, formal consensus was achieved for 100% (n = 61) of the terms and a glossary was then developed. Agreement between international experts has been reached on relevant terms and subsequent definitions regarding AS for patients with localized prostate cancer. This standard terminology could support multidisciplinary communication, reduce the extent of variations in clinical practice and optimize clinical decision making.
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U2 - 10.1038/nrurol.2017.26
DO - 10.1038/nrurol.2017.26
M3 - Review article
C2 - 28290462
AN - SCOPUS:85014988626
SN - 1759-4812
VL - 14
SP - 312
EP - 322
JO - Nature Reviews Urology
JF - Nature Reviews Urology
IS - 5
ER -
