Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure

I. Han; J. H. Choi; H. K. Baik; J. C. Park; J. K. Kim; K. Y. Lee; S. M. Chung; I. S. Lee

doi:10.4028/0-87849-967-9.425

Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure

I. Han, J. H. Choi, H. K. Baik, J. C. Park, J. K. Kim, K. Y. Lee, S. M. Chung, I. S. Lee

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Abstract

The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.

Original language	English
Pages (from-to)	425-428
Number of pages	4
Journal	Key Engineering Materials
Volume	288-289
DOIs	https://doi.org/10.4028/0-87849-967-9.425
Publication status	Published - 2005

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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title = "Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure",

abstract = "The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.",

author = "I. Han and Choi, {J. H.} and Baik, {H. K.} and Park, {J. C.} and Kim, {J. K.} and Lee, {K. Y.} and Chung, {S. M.} and Lee, {I. S.}",

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doi = "10.4028/0-87849-967-9.425",

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T1 - Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure

AU - Han, I.

AU - Choi, J. H.

AU - Baik, H. K.

AU - Park, J. C.

AU - Kim, J. K.

AU - Lee, K. Y.

AU - Chung, S. M.

AU - Lee, I. S.

PY - 2005

Y1 - 2005

N2 - The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.

AB - The surface properties of scaffolds are important since cell affinity is the most crucial factor to be concerned when the biodegradable polymeric material is utilized as a scaffold in tissue engineering. The surface of biodegradable non-porous poly (lactic-co-glycolic acid) (PLGA) scaffolds were treated by atmospheric pressure dielectric barrier discharge (APDBD). The wetting angle of APDBD treated PLGA were decreased from the untreated PLGA of 73° to 42°. FTIR-ATR analyses showed hydroxyl groups were not detected regardless of treated condition, but the intensities of both ether groups and carbonyl groups were increased with treatment time and oxygen flow rate. Treatment time and oxygen flux are equally effective to make the PLGA surface more hydrophilic.

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JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Evaluation of poly (lactic-co-glycolic acid) (65/35) treated by dielectric barrier discharge in atmospheric pressure

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