Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

Kyung Eun Han; Sang Chul Yoon; Ji Min Ahn; Sang Min Nam; R. Doyle Stulting; Eung Kweon Kim; Kyoung Yul Seo

doi:10.1016/j.ajo.2014.02.036

Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

Kyung Eun Han, Sang Chul Yoon, Ji Min Ahn, Sang Min Nam, R. Doyle Stulting, Eung Kweon Kim, Kyoung Yul Seo

Department of Ophthalmology

Research output: Contribution to journal › Article › peer-review

129 Citations (Scopus)

Abstract

• Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

Original language	English
Pages (from-to)	1144-1150.e1
Journal	American Journal of Ophthalmology
Volume	157
Issue number	6
DOIs	https://doi.org/10.1016/j.ajo.2014.02.036
Publication status	Published - 2014 Jun

Bibliographical note

Funding Information:
All authors have completed and submitted the ICMJE form for disclosure for potential conflicts of interest, and none were reported. This study was supported by a grant from the Korea Healthcare technology R&D Project , Ministry of Health & Welfare , Republic of Korea (Grant No. A121861 ). Involved in design of study (K.E.H., K.Y.S); Conduct of study (K.E.H., S.C.Y., K.Y.S); Collection, management, analysis, and interpretation of data (K.E.H., S.C.Y., S.M.N., J.M.A., K.Y.S); Preparation of manuscript (K.E.H., K.Y.S); Critical revision of article; (K.E.H., S.M.N., R.D.S., K.Y.S.); Final approval of manuscript (K.E.H., R.D.S., E.K.K., K.Y.S).

All Science Journal Classification (ASJC) codes

Ophthalmology

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10.1016/j.ajo.2014.02.036

Cite this

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title = "Evaluation of dry eye and meibomian gland dysfunction after cataract surgery",

abstract = "• Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.",

author = "Han, {Kyung Eun} and Yoon, {Sang Chul} and Ahn, {Ji Min} and Nam, {Sang Min} and Stulting, {R. Doyle} and Kim, {Eung Kweon} and Seo, {Kyoung Yul}",

note = "Funding Information: All authors have completed and submitted the ICMJE form for disclosure for potential conflicts of interest, and none were reported. This study was supported by a grant from the Korea Healthcare technology R&D Project , Ministry of Health & Welfare , Republic of Korea (Grant No. A121861 ). Involved in design of study (K.E.H., K.Y.S); Conduct of study (K.E.H., S.C.Y., K.Y.S); Collection, management, analysis, and interpretation of data (K.E.H., S.C.Y., S.M.N., J.M.A., K.Y.S); Preparation of manuscript (K.E.H., K.Y.S); Critical revision of article; (K.E.H., S.M.N., R.D.S., K.Y.S.); Final approval of manuscript (K.E.H., R.D.S., E.K.K., K.Y.S). ",

year = "2014",

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doi = "10.1016/j.ajo.2014.02.036",

language = "English",

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pages = "1144--1150.e1",

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T1 - Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

AU - Han, Kyung Eun

AU - Yoon, Sang Chul

AU - Ahn, Ji Min

AU - Nam, Sang Min

AU - Stulting, R. Doyle

AU - Kim, Eung Kweon

AU - Seo, Kyoung Yul

N1 - Funding Information: All authors have completed and submitted the ICMJE form for disclosure for potential conflicts of interest, and none were reported. This study was supported by a grant from the Korea Healthcare technology R&D Project , Ministry of Health & Welfare , Republic of Korea (Grant No. A121861 ). Involved in design of study (K.E.H., K.Y.S); Conduct of study (K.E.H., S.C.Y., K.Y.S); Collection, management, analysis, and interpretation of data (K.E.H., S.C.Y., S.M.N., J.M.A., K.Y.S); Preparation of manuscript (K.E.H., K.Y.S); Critical revision of article; (K.E.H., S.M.N., R.D.S., K.Y.S.); Final approval of manuscript (K.E.H., R.D.S., E.K.K., K.Y.S).

PY - 2014/6

Y1 - 2014/6

N2 - • Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

AB - • Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery. • Design: Prospective observational case series. • Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively. Ocular symptom scores, lid margin abnormalities, superficial punctate keratopathies (SPKs), tear film break-up time (TBUT), Schirmer test, lower tear meniscus height, depth, and area using Fourier domain optical coherence tomography, meibum expressibility and images of the meibomian glands using meibography were measured. • Results: The ocular symptom scores were worse at 1 month and 3 months postoperatively (P < 0.001 and P < 0.001, respectively). Lid margin abnormalities were significantly increased (P < 0.001 and P < 0.001, respectively) and TBUT decreased postoperatively (P < 0.001 and P < 0.001, respectively). Meibum expressibility decreased at 3 months postoperatively (P = 0.016); however, meibography score, SPK, lower tear meniscus height, depth and area and the Schirmer test did not change significantly postoperatively (all P values >0.05). • Conclusion: Meibomian gland function may be altered without accompanying structural changes after cataract surgery.

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SN - 0002-9394

VL - 157

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JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

IS - 6

ER -

Evaluation of dry eye and meibomian gland dysfunction after cataract surgery

Abstract

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