Evaluation of an immunochromatographic assay kit for rapid identification of Mycobacterium tuberculosis complex in clinical isolates

Young Park Mi; Jin Kim Young; Hyun Hwang Sang; Hoi Kim Hyoung; Yup Lee Eun; Hoon Jeong Seok; Chulhun L. Chang

doi:10.1128/JCM.01253-08

Evaluation of an immunochromatographic assay kit for rapid identification of Mycobacterium tuberculosis complex in clinical isolates

Young Park Mi, Jin Kim Young, Hyun Hwang Sang, Hoi Kim Hyoung, Yup Lee Eun, Hoon Jeong Seok, Chulhun L. Chang

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

We evaluated a new immunochromatographic assay (ICA) using mouse monoclonal anti-MPT64 antibody for rapid discrimination between Mycobacterium tuberculosis and nontuberculous mycobacteria in clinical isolates. A study with mycobacteria and other organisms showed excellent sensitivity (≅99%) and specificity (100%) and an appropriate detection limit (10⁵ CFU/ml) when tested with M. tuberculosis H37Rv. This ICA can simplify the identification of M. tuberculosis in clinical laboratories.

Original language	English
Pages (from-to)	481-484
Number of pages	4
Journal	Journal of Clinical Microbiology
Volume	47
Issue number	2
DOIs	https://doi.org/10.1128/JCM.01253-08
Publication status	Published - 2009 Feb

All Science Journal Classification (ASJC) codes

Microbiology (medical)

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10.1128/JCM.01253-08

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AU - Seok, Hoon Jeong

AU - Chang, Chulhun L.

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Evaluation of an immunochromatographic assay kit for rapid identification of Mycobacterium tuberculosis complex in clinical isolates

Abstract

All Science Journal Classification (ASJC) codes

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