Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica

Jung Sun Kim; Dong Ho Shin; Byeong Keuk Kim; Young Guk Ko; Donghoon Choi; Yangsoo Jang; Myeong Ki Hong

doi:10.1016/j.recesp.2014.07.026

Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica

Translated title of the contribution: Randomized comparison of stent strut coverage following angiography- or optical coherence tomography-guided percutaneous coronary intervention

Jung Sun Kim, Dong Ho Shin, Byeong Keuk Kim, Young Guk Ko, Donghoon Choi, Yangsoo Jang, Myeong Ki Hong

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Introduction and objectives The clinical benefits of optical coherence tomography-guided percutaneous coronary intervention are unclear. Therefore, in this study we sought to evaluate the impact of optical coherence tomography guidance on stent strut coverage following drug-eluting stent implantation. Methods A total of 101 patients in 105 lesions were randomly assigned to receive percutaneous coronary intervention under either optical coherence tomography guidance (n = 51 lesions of 50 patients) or angiography guidance (n = 54 lesions of 51 patients), and underwent a follow-up optical coherence tomography examination 6 months after zotarolimus-eluting stent implantation. The primary and secondary end points were the percentage of uncovered and malapposed struts, respectively, on 6-month follow-up optical coherence tomography. Results The percentage of uncovered struts was significantly lower in the optical coherence tomography-guided arm (1.60% [1.84]%, [median, 1.06%] vs 4.51% [5.43]% [median, 2.38%]; P =.0004) at 6-month follow-up. The incidence of stents with ≥ 5.9% uncovered struts was also significantly lower in the optical coherence tomography-guided arm (2 patients [3.9%] vs 14 patients [25.9%]; P =.002). In addition, the percentage of malapposed struts was significantly lower in the optical coherence tomography-guided arm (0.19% [0.51]% [median, 0.0%] vs 0.98% [2.53]% [median, 0.0%]; P =.027). Conclusions Optical coherence tomography-guided percutaneous coronary intervention significantly reduced the incidence of uncovered stent struts at 6 months compared to angiography-guided percutaneous coronary intervention. These findings suggest that optical coherence tomography-guided percutaneous coronary intervention has a beneficial effect on drug-eluting stent strut coverage. Full English text available from: www.revespcardiol.org/en

Translated title of the contribution	Randomized comparison of stent strut coverage following angiography- or optical coherence tomography-guided percutaneous coronary intervention
Original language	Spanish
Pages (from-to)	190-197
Number of pages	8
Journal	Revista Espanola de Cardiologia
Volume	68
Issue number	3
DOIs	https://doi.org/10.1016/j.recesp.2014.07.026
Publication status	Published - 2015 Mar 1

Bibliographical note

Publisher Copyright:
© 2014 Sociedad Española de Cardiología.

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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10.1016/j.recesp.2014.07.026

Cite this

Kim, J. S., Shin, D. H., Kim, B. K., Ko, Y. G., Choi, D., Jang, Y., & Hong, M. K. (2015). Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica. Revista Espanola de Cardiologia, 68(3), 190-197. https://doi.org/10.1016/j.recesp.2014.07.026

@article{d1f4d8ad536f47c68485c9ed6cf23f8b,

title = "Estudio aleatorizado de comparaci{\'o}n de la cobertura de los struts de los stents tras la intervenci{\'o}n coronaria percut{\'a}nea guiada por angiograf{\'i}a y la guiada por tomograf{\'i}a de coherencia {\'o}ptica",

abstract = "Introduction and objectives The clinical benefits of optical coherence tomography-guided percutaneous coronary intervention are unclear. Therefore, in this study we sought to evaluate the impact of optical coherence tomography guidance on stent strut coverage following drug-eluting stent implantation. Methods A total of 101 patients in 105 lesions were randomly assigned to receive percutaneous coronary intervention under either optical coherence tomography guidance (n = 51 lesions of 50 patients) or angiography guidance (n = 54 lesions of 51 patients), and underwent a follow-up optical coherence tomography examination 6 months after zotarolimus-eluting stent implantation. The primary and secondary end points were the percentage of uncovered and malapposed struts, respectively, on 6-month follow-up optical coherence tomography. Results The percentage of uncovered struts was significantly lower in the optical coherence tomography-guided arm (1.60% [1.84]%, [median, 1.06%] vs 4.51% [5.43]% [median, 2.38%]; P =.0004) at 6-month follow-up. The incidence of stents with ≥ 5.9% uncovered struts was also significantly lower in the optical coherence tomography-guided arm (2 patients [3.9%] vs 14 patients [25.9%]; P =.002). In addition, the percentage of malapposed struts was significantly lower in the optical coherence tomography-guided arm (0.19% [0.51]% [median, 0.0%] vs 0.98% [2.53]% [median, 0.0%]; P =.027). Conclusions Optical coherence tomography-guided percutaneous coronary intervention significantly reduced the incidence of uncovered stent struts at 6 months compared to angiography-guided percutaneous coronary intervention. These findings suggest that optical coherence tomography-guided percutaneous coronary intervention has a beneficial effect on drug-eluting stent strut coverage. Full English text available from: www.revespcardiol.org/en",

author = "Kim, {Jung Sun} and Shin, {Dong Ho} and Kim, {Byeong Keuk} and Ko, {Young Guk} and Donghoon Choi and Yangsoo Jang and Hong, {Myeong Ki}",

note = "Publisher Copyright: {\textcopyright} 2014 Sociedad Espa{\~n}ola de Cardiolog{\'i}a.",

year = "2015",

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day = "1",

doi = "10.1016/j.recesp.2014.07.026",

language = "Spanish",

volume = "68",

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Kim, JS, Shin, DH, Kim, BK, Ko, YG, Choi, D , Jang, Y & Hong, MK 2015, 'Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica', Revista Espanola de Cardiologia, vol. 68, no. 3, pp. 190-197. https://doi.org/10.1016/j.recesp.2014.07.026

Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica. / Kim, Jung Sun; Shin, Dong Ho; Kim, Byeong Keuk et al.
In: Revista Espanola de Cardiologia, Vol. 68, No. 3, 01.03.2015, p. 190-197.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica

AU - Kim, Jung Sun

AU - Shin, Dong Ho

AU - Kim, Byeong Keuk

AU - Ko, Young Guk

AU - Choi, Donghoon

AU - Jang, Yangsoo

AU - Hong, Myeong Ki

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Introduction and objectives The clinical benefits of optical coherence tomography-guided percutaneous coronary intervention are unclear. Therefore, in this study we sought to evaluate the impact of optical coherence tomography guidance on stent strut coverage following drug-eluting stent implantation. Methods A total of 101 patients in 105 lesions were randomly assigned to receive percutaneous coronary intervention under either optical coherence tomography guidance (n = 51 lesions of 50 patients) or angiography guidance (n = 54 lesions of 51 patients), and underwent a follow-up optical coherence tomography examination 6 months after zotarolimus-eluting stent implantation. The primary and secondary end points were the percentage of uncovered and malapposed struts, respectively, on 6-month follow-up optical coherence tomography. Results The percentage of uncovered struts was significantly lower in the optical coherence tomography-guided arm (1.60% [1.84]%, [median, 1.06%] vs 4.51% [5.43]% [median, 2.38%]; P =.0004) at 6-month follow-up. The incidence of stents with ≥ 5.9% uncovered struts was also significantly lower in the optical coherence tomography-guided arm (2 patients [3.9%] vs 14 patients [25.9%]; P =.002). In addition, the percentage of malapposed struts was significantly lower in the optical coherence tomography-guided arm (0.19% [0.51]% [median, 0.0%] vs 0.98% [2.53]% [median, 0.0%]; P =.027). Conclusions Optical coherence tomography-guided percutaneous coronary intervention significantly reduced the incidence of uncovered stent struts at 6 months compared to angiography-guided percutaneous coronary intervention. These findings suggest that optical coherence tomography-guided percutaneous coronary intervention has a beneficial effect on drug-eluting stent strut coverage. Full English text available from: www.revespcardiol.org/en

AB - Introduction and objectives The clinical benefits of optical coherence tomography-guided percutaneous coronary intervention are unclear. Therefore, in this study we sought to evaluate the impact of optical coherence tomography guidance on stent strut coverage following drug-eluting stent implantation. Methods A total of 101 patients in 105 lesions were randomly assigned to receive percutaneous coronary intervention under either optical coherence tomography guidance (n = 51 lesions of 50 patients) or angiography guidance (n = 54 lesions of 51 patients), and underwent a follow-up optical coherence tomography examination 6 months after zotarolimus-eluting stent implantation. The primary and secondary end points were the percentage of uncovered and malapposed struts, respectively, on 6-month follow-up optical coherence tomography. Results The percentage of uncovered struts was significantly lower in the optical coherence tomography-guided arm (1.60% [1.84]%, [median, 1.06%] vs 4.51% [5.43]% [median, 2.38%]; P =.0004) at 6-month follow-up. The incidence of stents with ≥ 5.9% uncovered struts was also significantly lower in the optical coherence tomography-guided arm (2 patients [3.9%] vs 14 patients [25.9%]; P =.002). In addition, the percentage of malapposed struts was significantly lower in the optical coherence tomography-guided arm (0.19% [0.51]% [median, 0.0%] vs 0.98% [2.53]% [median, 0.0%]; P =.027). Conclusions Optical coherence tomography-guided percutaneous coronary intervention significantly reduced the incidence of uncovered stent struts at 6 months compared to angiography-guided percutaneous coronary intervention. These findings suggest that optical coherence tomography-guided percutaneous coronary intervention has a beneficial effect on drug-eluting stent strut coverage. Full English text available from: www.revespcardiol.org/en

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Estudio aleatorizado de comparación de la cobertura de los struts de los stents tras la intervención coronaria percutánea guiada por angiografía y la guiada por tomografía de coherencia óptica

Abstract

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