Abstract
The immobilization of glucose oxidase (GOx) on indium-gallium zinc oxide (IGZO) thin films is studied in order to fabricate a high performance biosensor. An amine functionalized layer, using (3-aminopropyl)triethoxysilane (APTES), is employed to support the immobilization and to achieve a qualified silanization layer. Fourier Transform Infrared (FT-IR) Spectroscopy, Atomic Force Microscopy (AFM), and contact angle measurements were performed to analyze the surface characteristics and to investigate a deposition mechanism for APTES with varying concentrations. Finally, GOx is immobilized on the APTES layer to determine how a diverse surface quality influences GOx density, and its enzymatic activity is identified by the detection of the electrical signal from glucose biosensors.
| Original language | English |
|---|---|
| Pages (from-to) | 19656-19661 |
| Number of pages | 6 |
| Journal | RSC Advances |
| Volume | 7 |
| Issue number | 32 |
| DOIs | |
| Publication status | Published - 2017 |
Bibliographical note
Publisher Copyright:© The Royal Society of Chemistry.
All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Chemical Engineering(all)