Enantioselective radical addition to ketimines: A synthetic route towards α,α-disubstituted α-amino acids

Sang Yoon Kim; Sung Jun Kim; Doo Ok Jang

doi:10.1002/chem.201002071

Enantioselective radical addition to ketimines: A synthetic route towards α,α-disubstituted α-amino acids

Sang Yoon Kim, Sung Jun Kim, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A radical attack: In the presence of a protonated cinchonine derivative, radical addition reactions proceeded efficiently, providing a general approach to the synthesis of a diverse range of enantioenriched α,α- disubstituted α-amino acids.

Original language	English
Pages (from-to)	13046-13048
Number of pages	3
Journal	Chemistry - A European Journal
Volume	16
Issue number	44
DOIs	https://doi.org/10.1002/chem.201002071
Publication status	Published - 2010 Nov 22

Bibliographical note

Funding Information:
This research was partly supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2014R1A1A1005969) and Institute for Information & communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) (No. R0190-16-2012).

All Science Journal Classification (ASJC) codes

Catalysis
Organic Chemistry

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10.1002/chem.201002071

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title = "Enantioselective radical addition to ketimines: A synthetic route towards α,α-disubstituted α-amino acids",

abstract = "A radical attack: In the presence of a protonated cinchonine derivative, radical addition reactions proceeded efficiently, providing a general approach to the synthesis of a diverse range of enantioenriched α,α- disubstituted α-amino acids.",

author = "Kim, {Sang Yoon} and Kim, {Sung Jun} and Jang, {Doo Ok}",

note = "Funding Information: This research was partly supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2014R1A1A1005969) and Institute for Information & communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) (No. R0190-16-2012).",

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AU - Kim, Sang Yoon

AU - Kim, Sung Jun

AU - Jang, Doo Ok

N1 - Funding Information: This research was partly supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2014R1A1A1005969) and Institute for Information & communications Technology Promotion (IITP) grant funded by the Korea government (MSIP) (No. R0190-16-2012).

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Enantioselective radical addition to ketimines: A synthetic route towards α,α-disubstituted α-amino acids

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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