Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression

Adam E. Mendrela; Jihyun Cho; Jeffrey A. Fredenburg; Cynthia A. Chestek; Michael P. Flynn; Euisik Yoon

doi:10.1109/VLSIC.2015.7231342

Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression

Adam E. Mendrela, Jihyun Cho, Jeffrey A. Fredenburg, Cynthia A. Chestek, Michael P. Flynn, Euisik Yoon

Yonsei Advanced Science Institute

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

10 Citations (Scopus)

Abstract

We present the first bi-directional neural interface chip that employs a stimulation artifact cancellation circuit to allow concurrent recording and stimulation. In order to further suppress cross-channel common-mode noise, we incorporated a novel common average referencing (CAR) circuit in conjunction with range-adapting (RA) SAR ADC for low-power implementation. The fabricated prototype attenuates stimulation artifacts by up to 42 dB and suppresses common noise among channels by up to 39.8 dB at 330 nW and in an area of 0.17 mm² per channel.

Original language	English
Title of host publication	2015 Symposium on VLSI Circuits, VLSI Circuits 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	C108-C109
ISBN (Electronic)	9784863485020
DOIs	https://doi.org/10.1109/VLSIC.2015.7231342
Publication status	Published - 2015 Aug 31
Event	29th Annual Symposium on VLSI Circuits, VLSI Circuits 2015 - Kyoto, Japan Duration: 2015 Jun 17 → 2015 Jun 19

Publication series

Name	IEEE Symposium on VLSI Circuits, Digest of Technical Papers
Volume	2015-August

Conference

Conference	29th Annual Symposium on VLSI Circuits, VLSI Circuits 2015
Country/Territory	Japan
City	Kyoto
Period	15/6/17 → 15/6/19

Bibliographical note

Publisher Copyright:
© 2015 JSAP.

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

Access to Document

10.1109/VLSIC.2015.7231342

Cite this

Mendrela, A. E., Cho, J., Fredenburg, J. A., Chestek, C. A., Flynn, M. P., & Yoon, E. (2015). Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression. In 2015 Symposium on VLSI Circuits, VLSI Circuits 2015 (pp. C108-C109). [7231342] (IEEE Symposium on VLSI Circuits, Digest of Technical Papers; Vol. 2015-August). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/VLSIC.2015.7231342

Mendrela, Adam E. ; Cho, Jihyun ; Fredenburg, Jeffrey A. et al. / Enabling closed-loop neural interface : A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression. 2015 Symposium on VLSI Circuits, VLSI Circuits 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. C108-C109 (IEEE Symposium on VLSI Circuits, Digest of Technical Papers).

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title = "Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression",

abstract = "We present the first bi-directional neural interface chip that employs a stimulation artifact cancellation circuit to allow concurrent recording and stimulation. In order to further suppress cross-channel common-mode noise, we incorporated a novel common average referencing (CAR) circuit in conjunction with range-adapting (RA) SAR ADC for low-power implementation. The fabricated prototype attenuates stimulation artifacts by up to 42 dB and suppresses common noise among channels by up to 39.8 dB at 330 nW and in an area of 0.17 mm2 per channel.",

author = "Mendrela, {Adam E.} and Jihyun Cho and Fredenburg, {Jeffrey A.} and Chestek, {Cynthia A.} and Flynn, {Michael P.} and Euisik Yoon",

note = "Publisher Copyright: {\textcopyright} 2015 JSAP.; 29th Annual Symposium on VLSI Circuits, VLSI Circuits 2015 ; Conference date: 17-06-2015 Through 19-06-2015",

year = "2015",

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doi = "10.1109/VLSIC.2015.7231342",

language = "English",

series = "IEEE Symposium on VLSI Circuits, Digest of Technical Papers",

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Mendrela, AE, Cho, J, Fredenburg, JA, Chestek, CA, Flynn, MP & Yoon, E 2015, Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression. in 2015 Symposium on VLSI Circuits, VLSI Circuits 2015., 7231342, IEEE Symposium on VLSI Circuits, Digest of Technical Papers, vol. 2015-August, Institute of Electrical and Electronics Engineers Inc., pp. C108-C109, 29th Annual Symposium on VLSI Circuits, VLSI Circuits 2015, Kyoto, Japan, 15/6/17. https://doi.org/10.1109/VLSIC.2015.7231342

Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression. / Mendrela, Adam E.; Cho, Jihyun; Fredenburg, Jeffrey A. et al.
2015 Symposium on VLSI Circuits, VLSI Circuits 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. C108-C109 7231342 (IEEE Symposium on VLSI Circuits, Digest of Technical Papers; Vol. 2015-August).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Mendrela AE, Cho J, Fredenburg JA, Chestek CA, Flynn MP, Yoon E. Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression. In 2015 Symposium on VLSI Circuits, VLSI Circuits 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. C108-C109. 7231342. (IEEE Symposium on VLSI Circuits, Digest of Technical Papers). doi: 10.1109/VLSIC.2015.7231342

Enabling closed-loop neural interface: A bi-directional interface circuit with stimulation artifact cancellation and cross-channel CM noise suppression

Abstract

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Bibliographical note

All Science Journal Classification (ASJC) codes

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