Elevated leukocyte count is associated with periodontitis in Korean adults: the 2012–2014 KNHANES

Y. J. Kwon, K. J. Jeon, T. H. Chung, Y. J. Lee

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Objective: Both an elevated leukocyte count and periodontitis share well-recognized associations with cardiometabolic diseases. This cross-sectional study aimed to identify whether the leukocyte count is associated with periodontitis in a nationally representative Korean adult population. Materials and Methods: Data from 9391 participants (3659 males and 5732 females) enrolled in 2012–2014 Korean National Health and Nutrition Examination Survey were analyzed. Leukocyte quartiles were categorized as follows: 3000 ≤ Q1 ≤ 4870, 4880 ≤ Q2 ≤5790, 5800 ≤ Q3 ≤ 6840, and 6850 ≤ Q4 ≤ 10000 cells/μl. Periodontitis was defined as scoring greater than or equal to ‘code 3’ in at least one site according to the WHO's Community Periodontal Index. The odds ratios (ORs) and 95% confidence intervals (95% CIs) for periodontitis in each leukocyte count quartile were calculated using multiple logistic regression analyses. Results: The prevalence of periodontitis was directly correlated with increasing leukocyte quartiles: 19%, 20.4%, 24.3%, and 30.3%. Compared with the lowest leukocyte quartile group, the OR (95% CI) for periodontitis of the highest leukocyte quartile was 1.558 (1.285–1.891) after controlling for confounding factors. Conclusion: An elevated leukocyte count was positively associated with the presence of periodontitis.

Original languageEnglish
Pages (from-to)241-246
Number of pages6
JournalOral Diseases
Issue number2
Publication statusPublished - 2017 Mar 1

Bibliographical note

Publisher Copyright:
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Dentistry(all)


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