Effects of (1→3), (1→6)-β-D-glucan behavior in human dermal fibroblast cells under serum starvation

Yeon I. Woo; Hyun Joo Son; Hye Ryeon Lim; Mi Hee Lee; Hyun Sook Baek; Kazufumi Tsubaki; Jong Chul Park

doi:10.4028/0-87849-436-7.401

Effects of (1→3), (1→6)-β-D-glucan behavior in human dermal fibroblast cells under serum starvation

Yeon I. Woo, Hyun Joo Son, Hye Ryeon Lim, Mi Hee Lee, Hyun Sook Baek, Kazufumi Tsubaki, Jong Chul Park

Department of Medical Engineering

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.

Original language	English
Pages (from-to)	401-404
Number of pages	4
Journal	Key Engineering Materials
Volume	342-343
DOIs	https://doi.org/10.4028/0-87849-436-7.401
Publication status	Published - 2007

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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title = "Effects of (1→3), (1→6)-β-D-glucan behavior in human dermal fibroblast cells under serum starvation",

abstract = "Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.",

author = "Woo, {Yeon I.} and Son, {Hyun Joo} and Lim, {Hye Ryeon} and Lee, {Mi Hee} and Baek, {Hyun Sook} and Kazufumi Tsubaki and Park, {Jong Chul}",

year = "2007",

doi = "10.4028/0-87849-436-7.401",

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volume = "342-343",

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T1 - Effects of (1→3), (1→6)-β-D-glucan behavior in human dermal fibroblast cells under serum starvation

AU - Woo, Yeon I.

AU - Son, Hyun Joo

AU - Lim, Hye Ryeon

AU - Lee, Mi Hee

AU - Baek, Hyun Sook

AU - Tsubaki, Kazufumi

AU - Park, Jong Chul

PY - 2007

Y1 - 2007

N2 - Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.

AB - Glucans have been reported to stimulate immunity and to promote wound healing. Adult human dermal fibroblast (aHDF) cultured in serum free (serum-starvation). Proliferation of aHDF was measured at various concentrations of β-glucan by MTT assay, and migration was observed for 36h on microscope. The result of fibroblast bioassay, β-glucan had positive influence. In this study, the direct effects of β-glucan on proliferation and migration of human dermal fibroblasts were examined in vitro. That means β-D-glucan has the effect to enhance proliferation and aHDF migration speed, and has the potential as a wound healing agent.

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Effects of (1→3), (1→6)-β-D-glucan behavior in human dermal fibroblast cells under serum starvation

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