Effect of intraoperative fluid volume on postoperative ileus after robot-assisted radical cystectomy

Ji Sung Shim, Tae Il Noh, Ja Hyeon Ku, Sangchul Lee, Tae Gyun Kwon, Tae Hwan Kim, Seung Hyun Jeon, Sang Hyup Lee, Jong Kil Nam, Wan Seok Kim, Byong Chang Jeong, Ji Youl Lee, Sung Hoo Hong, Koon Ho Rha, Woong Kyu Han, Won Sik Ham, Young Goo Lee, Yong Seong Lee, Sung Yul Park, Young Eun YoonSung Gu Kang, Jong Jin Oh, Seok Ho Kang, Tae Hwan Kim, Jong Kil Nam, Tae Gyun Kwon, Yong Seong Lee, Sung Yul Park, Young Eun Yoon, Jong Jin Oh, Sung Gu Kang, Jong Jin Oh, Young Goo Lee

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5 Citations (Scopus)


This study aimed to investigate the effect of intraoperative fluid volume on the postoperative ileus (POI) recovery period. A retrospective review of the Korean robot-assisted radical cystectomy database identified 718 patients who underwent robot-assisted radical cystectomy (RARC). Regression analyses were performed to identify the associations between the amount of intraoperative fluid administration (crystalloid/colloid/total), POI period (time to flatus/bowel movements), and length of hospital stay (LOS) after adjusting for covariates. In addition, we analyzed the risk factors for gastrointestinal complications and prolonged POI using a logistic regression model. An increasing volume of the administered crystalloid/total fluid was associated with prolonged POI (crystalloid R2 = 0.0725 and P < 0.0001; total amount R2 = 0.0812 and P < 0.0001), and the total fluid volume was positively associated with the LOS (R2 = 0.099 and P < 0.0001). The crystalloid amount was a risk factor for prolonged POI (P < 0.001; odds ratio, 1.361; 95% confidence interval, 1.133–1.641; P < 0.001). In the context of RARC, increased intravenous fluids are associated with prolonged POI and longer LOS.

Original languageEnglish
Article number10522
JournalScientific reports
Issue number1
Publication statusPublished - 2021 Dec 1

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© 2021, The Author(s).

All Science Journal Classification (ASJC) codes

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