TY - JOUR
T1 - DNA-based nanostructures for molecular sensing
AU - Lee, Jong Bum
AU - Campolongo, Michael John
AU - Kahn, Jason Samuel
AU - Roh, Young Hoon
AU - Hartman, Mark Richard
AU - Luo, Dan
PY - 2010/2/9
Y1 - 2010/2/9
N2 - Nanotechnology has opened up new avenues towards ultra-sensitive, highly selective detection of biological molecules and toxic agents, as well as for therapeutic targeting and screening. Though the goals may seem singular, there is no universal method to identify or detect a molecular target. Each system is application-specific and must not only identify the target, but also transduce this interaction into a meaningful signal rapidly, reliably, and inexpensively. This review focuses on the current capabilities and future directions of DNA-based nanostructures in sensing and detection.
AB - Nanotechnology has opened up new avenues towards ultra-sensitive, highly selective detection of biological molecules and toxic agents, as well as for therapeutic targeting and screening. Though the goals may seem singular, there is no universal method to identify or detect a molecular target. Each system is application-specific and must not only identify the target, but also transduce this interaction into a meaningful signal rapidly, reliably, and inexpensively. This review focuses on the current capabilities and future directions of DNA-based nanostructures in sensing and detection.
UR - http://www.scopus.com/inward/record.url?scp=78049372772&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78049372772&partnerID=8YFLogxK
U2 - 10.1039/b9nr00142e
DO - 10.1039/b9nr00142e
M3 - Article
C2 - 20644794
AN - SCOPUS:78049372772
SN - 2040-3364
VL - 2
SP - 188
EP - 197
JO - Nanoscale
JF - Nanoscale
IS - 2
ER -