Dissolution behavior and early bone apposition of calcium phosphate-coated machined implants

Ji Wan Hwang, Eun Ung Lee, Jung Seok Lee, Ui Won Jung, In Seop Lee, Seong Ho Choi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Purpose: Calcium phosphate (CaP)-coated implants promote osseointegration and survival rate. The aim of this study was to (1) analyze the dissolution behavior of the residual CaP particles of removed implants and (2) evaluate bone apposition of CaPcoated machined surface implants at the early healing phase. Methods: Mandibular premolars were extracted from five dogs. After eight weeks, the implants were placed according to drilling protocols: a nonmobile implant (NI) group and rotational implant (RI) group. For CaP dissolution behavior analysis, 8 implants were removed after 0, 1, 2, and 4 weeks. The surface morphology and deposition of the coatings were observed. For bone apposition analysis, block sections were obtained after 1-, 2-, and 4-week healing periods and the specimens were analyzed. Results: Calcium and phosphorus were detected in the implants that were removed immediately after insertion, and the other implants were composed mainly of titanium. There were no notable differences between the NI and RI groups in terms of the healing process. The bone-to-implant contact and bone density in the RI group showed a remarkable increase after 2 weeks of healing. Conclusions: It can be speculated that the CaP coating dissolves early in the healing phase and chemically induces early bone formation regardless of the primary stability.

Original languageEnglish
Pages (from-to)291-300
Number of pages10
JournalJournal of Periodontal and Implant Science
Issue number6
Publication statusPublished - 2013 Dec

All Science Journal Classification (ASJC) codes

  • Oral Surgery
  • Periodontics


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