Direct photo-thermal diagnosis of anemia using platinum resistance temperature detector

Bong Seop Kwak, Hyung Joon Kim, Hyun Ok Kim, Hyo Il Jung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)


This article presents a thermal biosensor to diagnose anemia without chemical treatments using temperature increases of red blood cells when hemoglobin molecules absorb photons of specific wavelengths and convert them to thermal energy. For measuring the temperature changes, a micro-scaled platinum resistance temperature detector was developed. We also designed and fabricated a thermostat system to maintain a constant ambient temperature (<±0.1°C). An 8.0W/cm2 diode pumped solid state (DPSS) continuous wave (CW) laser module with a wavelength of 532 nm was used to heat the red blood cells. Using this system, we successfully measured temperature variations of whole blood samples from 10 anemic patients and subsequently determined the concentration of hemoglobin. The method proposed in this paper requires significantly smaller quantities of whole blood (6μl), as compared with conventional methods (175μl), and allows instantaneous diagnosis (6 seconds) of anemia.

Original languageEnglish
Title of host publicationIEEE Sensors 2010 Conference, SENSORS 2010
Number of pages4
Publication statusPublished - 2010
Event9th IEEE Sensors Conference 2010, SENSORS 2010 - Waikoloa, HI, United States
Duration: 2010 Nov 12010 Nov 4

Publication series

NameProceedings of IEEE Sensors


Other9th IEEE Sensors Conference 2010, SENSORS 2010
Country/TerritoryUnited States
CityWaikoloa, HI

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering


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