Diagnostic accuracy of manual office blood pressure measurement in ambulatory hypertensive patients in Korea

Sehun Kim, Jin Joo Park, Seung Ah Lee, Youngjin Cho, Yeonyee E. Yoon, Il Young Oh, Chang Hwan Yoon, Jung Won Suh, Young Seok Cho, Tae Jin Youn, Goo Yeong Cho, In Ho Chae, Hae Young Lee, Jinho Shin, Sungha Park, Dong Ju Choi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Background/Aims: Currently, office blood pressure (OBP) is the most widely used method of measuring blood pressure (BP) in daily clinical practice. However, data on the diagnostic accuracy of OBP in reference to ambulatory blood pressure (ABP) are scarce in Korea. Methods: In retrospective and prospective cohorts, manual OBP and ABP measurements were compared among ambulatory hypertensive patients. Hypertension was defined as systolic OBP ≥ 140 mmHg and/or diastolic OBP ≥ 90 mmHg, and systolic ABP ≥ 130 mmHg and/or diastolic ABP ≥ 80 mmHg. Results: In the retrospective cohort (n = 903), the mean OBP1 (before ABP mea-surement) was higher than ABP in both systolic (138 ± 17 mmHg vs. 123 ± 13 mmHg, p < 0.001) and diastolic (84 ± 12 mmHg vs. 78 ± 11 mmHg, p < 0.001) measurements. Interestingly, there was only a weak correlation between OBP and ABP (r 2 = 0.038, p < 0.001). The overall discordance rate of OBP compared to ABP, which is the reference method for measuring BP, was 43.9%. The prospective cohort (n = 57) showed similar results. In a subgroup analysis, male patients had higher false negative results (masked or under-treated hypertension) than did female patients (26.1% vs. 17.8%, p = 0.003), whereas female patients had a higher false positive rate (white-coat or over-treated hypertension) than did male patients (28.7% vs. 15.2%, p < 0.001). Conclusions: The diagnostic accuracy of manual OBP is low in reference to ABP. Men and women have different patterns of discordance. These findings indicate that management of hypertensive patients with manual OBP measurements may be suboptimal and encourages the use of ABP in ambulatory hypertensive patients.

Original languageEnglish
Pages (from-to)113-120
Number of pages8
JournalKorean Journal of Internal Medicine
Issue number1
Publication statusPublished - 2018 Jan

Bibliographical note

Publisher Copyright:
© 2018 The Korean Association of Internal Medicine.

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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