Development of a reusable colorimetric calcium sensor based on a calix[4]arene-functionalised glass surface

Yerim Yeon, Bo Hyeong Kim, Sung Kuk Kim, Sera Lee, Jong Seung Kim, Chul Ho Jun, Jonathan L. Sessler

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A dual functional chromogenic calix[4]arene that contains both hydroxy azophenols and triazoles for colorimetric sensing and cationic recognition, respectively, has been synthesised. This system was further functionalised with dimethallylsilane to permit grafting to a glass surface. This grafting may be used to produce a surface modified glass slides that act as reusable ion-selective colorimetric sensors. UV-vis spectral studies revealed that this compound is capable of binding the calcium cation in aqueous media and producing an easily detectable colour change. The same is true for the modified surface set-up. For the free receptor in acetonitrile solution, the absorption maximum undergoes a red shift from 390 to 496 nm upon exposure to calcium cations. In the case of the modified surface, exposure to acetonitrile solution of calcium perchlorate leads to a change in colour from orange to red. Washing with acetone serves to remove the metal cations from the calix[4]arene-functionalised glass and restore the original orange colour. Then the system is ready for reuse. Specifically, following treatment with acetone, the glass may be submerged in a metal solution once again. In the case of exposure to calcium salts, this re-exposure results in a colour change analogous to what was seen for a pristine system. This process may be repeated several times.

Original languageEnglish
Pages (from-to)121-126
Number of pages6
JournalSupramolecular Chemistry
Issue number2
Publication statusPublished - 2013 Feb 1

Bibliographical note

Funding Information:
This work was supported by the U.S. Department of Energy, Office of Basic Energy Sciences (grant DE-FG02-01ER15186 to J.L.S.), the World Class University (WCU) program (R32-2012-000-10217-0) through the National Research Foundation of Korea (NRF) (2011-0016830) funded by the Ministry of Education, Science and Technology (MEST) and the Robert A. Welch Foundation (grant F-1018 to J.L.S.).

All Science Journal Classification (ASJC) codes

  • Chemistry(all)


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