TY - JOUR
T1 - Determinants of coronary blood flow following primary angioplasty for acute myocardial infarction
AU - Lee, Cheol Whan
AU - Hong, Myeong Ki
AU - Kim, Hyun Sook
AU - Rhee, Kyoung Suk
AU - Kim, Jae Joong
AU - Park, Seong Wook
AU - Park, Seung Jung
PY - 2000
Y1 - 2000
N2 - The aim of this study was to evaluate determinants of coronary blood flow following primary angioplasty (PA) in acute myocardial infarction (AMI). The corrected TJMI (thrombolysis in myocardial infarction) frame count and the TIMI flow grade were used as indexes of coronary blood flow, and its determinants were examined in 115 consecutive AMI patients who underwent PA (pain onset ≤ 12 hr). The following were validated as univariate predictors of slower corrected TIMI frame count: A lower pressure-derived farctional collateral flow (PDCF) index (P < 0.01), poor angiographic collaterals (P < 0.01), TIMI flow 0, 1 before PA (P < 0.05), and the presence of heavy thrombi (P < 0.01). The PDCF index and the presence of heavy thrombi were independent predictors of i he corrected TIMI frame count. Likewise, the PDCF index (X2 = 12.9; P < 0.01) and the presence of heavy thombi (X2 = 11.4; P < 0.01) were independent predictors of TIMI 3 flow. In conclusion, collateral flow and the presence of thrombi are major determinants of coronary blood flow after PA in AMI. (C) 2000 Wiley-Liss, Inc.
AB - The aim of this study was to evaluate determinants of coronary blood flow following primary angioplasty (PA) in acute myocardial infarction (AMI). The corrected TJMI (thrombolysis in myocardial infarction) frame count and the TIMI flow grade were used as indexes of coronary blood flow, and its determinants were examined in 115 consecutive AMI patients who underwent PA (pain onset ≤ 12 hr). The following were validated as univariate predictors of slower corrected TIMI frame count: A lower pressure-derived farctional collateral flow (PDCF) index (P < 0.01), poor angiographic collaterals (P < 0.01), TIMI flow 0, 1 before PA (P < 0.05), and the presence of heavy thrombi (P < 0.01). The PDCF index and the presence of heavy thrombi were independent predictors of i he corrected TIMI frame count. Likewise, the PDCF index (X2 = 12.9; P < 0.01) and the presence of heavy thombi (X2 = 11.4; P < 0.01) were independent predictors of TIMI 3 flow. In conclusion, collateral flow and the presence of thrombi are major determinants of coronary blood flow after PA in AMI. (C) 2000 Wiley-Liss, Inc.
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U2 - 10.1002/1522-726X(200012)51:4<402::AID-CCD6>3.0.CO;2-M
DO - 10.1002/1522-726X(200012)51:4<402::AID-CCD6>3.0.CO;2-M
M3 - Article
C2 - 11108669
AN - SCOPUS:0033662139
SN - 1522-1946
VL - 51
SP - 402
EP - 406
JO - Catheterization and Cardiovascular Interventions
JF - Catheterization and Cardiovascular Interventions
IS - 4
ER -