Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology

Kalyaneswar Mandal; Brad L. Pentelute; Duhee Bang; Zachary P. Gates; Vladimir Yu Torbeev; Stephen B.H. Kent

doi:10.1002/anie.201107846

Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology

Kalyaneswar Mandal, Brad L. Pentelute, Duhee Bang, Zachary P. Gates, Vladimir Yu Torbeev, Stephen B.H. Kent

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Lassoed at the other end: Original synthetic and structure determination methods were used to make a protein molecule with an unprecedented linear-loop polypeptide chain topology, and to characterize its X-ray structure.

Original language	English
Pages (from-to)	1481-1486
Number of pages	6
Journal	Angewandte Chemie - International Edition
Volume	51
Issue number	6
DOIs	https://doi.org/10.1002/anie.201107846
Publication status	Published - 2012 Feb 6

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/anie.201107846

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title = "Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology",

abstract = "Lassoed at the other end: Original synthetic and structure determination methods were used to make a protein molecule with an unprecedented linear-loop polypeptide chain topology, and to characterize its X-ray structure.",

author = "Kalyaneswar Mandal and Pentelute, {Brad L.} and Duhee Bang and Gates, {Zachary P.} and Torbeev, {Vladimir Yu} and Kent, {Stephen B.H.}",

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AU - Pentelute, Brad L.

AU - Bang, Duhee

AU - Gates, Zachary P.

AU - Torbeev, Vladimir Yu

AU - Kent, Stephen B.H.

PY - 2012/2/6

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Design, total chemical synthesis, and X-ray structure of a protein having a novel linear-loop polypeptide chain topology

Abstract

All Science Journal Classification (ASJC) codes

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