Design and applications of molecular probes containing porphyrin derivatives

Hosoowi Lee, Kyeong Im Hong, Woo Dong Jang

Research output: Contribution to journalReview articlepeer-review

111 Citations (Scopus)


Porphyrins are heterocyclic macrocycle organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges. Because of their unique properties, synthetic porphyrin derivatives are powerful tools for molecular recognition. The optical or electronic monitoring of porphyrin derivatives permits the detection of the binding of transition metals. The binding of the metal ion to the porphyrin center provides additional axial ligand binding sites, which can be utilized for molecular recognition and sensing. Because of the large extinction coefficient and emission property, porphyrin derivatives can be utilized as fluorescent chromophores for the detection of various chemicals. In this paper, important development in terms of porphyrin-based chemical probes will be reviewed. This review is divided into nine sections focusing on porphyrin-based probes for (i) cations, (ii) anions, (iii) ion pairs, (iv) volatile organic chemicals, (v) nitroaromatic compounds, (vi) gases, (vii), reactive oxygen species, (viii) chiral discrimination, and (ix) environmental change detection, respectively.

Original languageEnglish
Pages (from-to)46-73
Number of pages28
JournalCoordination Chemistry Reviews
Publication statusPublished - 2018 Jan 1

Bibliographical note

Publisher Copyright:
© 2017 Elsevier B.V.

All Science Journal Classification (ASJC) codes

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry


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