Dendrimer porphyrin-based self-assembled nano-devices for biomedical applications

Young Hwan Jeong; Hee Jae Yoon; Woo Dong Jang

doi:10.1038/pj.2012.20

Dendrimer porphyrin-based self-assembled nano-devices for biomedical applications

Young Hwan Jeong, Hee Jae Yoon, Woo Dong Jang

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

20 Citations (Scopus)

Abstract

Dendrimers have attracted great interest for the design of functional materials. Because the core porphyrin unit in dendrimer porphyrin (DP) is surrounded by large poly(benzyl ether) dendritic wedges with ionic peripheries, the resulting electrostatic interaction with oppositely charged polymeric materials has been used to create various functional nano-devices. In this paper, we briefly review DP-based self-assembled biomedical nano-devices, including DP-loaded polyion complex micelles, the ternary complex systems used for gene delivery, polymer-metal complex micelles, the hollow nanocapsules used for combination cancer therapy, and the DP-immobilized surfaces used for diagnostic tools.

Original language	English
Pages (from-to)	512-521
Number of pages	10
Journal	Polymer Journal
Volume	44
Issue number	6
DOIs	https://doi.org/10.1038/pj.2012.20
Publication status	Published - 2012 Jun

Bibliographical note

Funding Information:
This work was supported by a National Research Foundation (NRF) grant funded by the Korean government (MEST) (no. 2011-0001126). Y.-H. Jeong and H.-J. Yoon acknowledge fellowships from the BK21 program supported by MEST, Korea.

All Science Journal Classification (ASJC) codes

Polymers and Plastics
Materials Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/pj.2012.20

Cite this

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title = "Dendrimer porphyrin-based self-assembled nano-devices for biomedical applications",

abstract = "Dendrimers have attracted great interest for the design of functional materials. Because the core porphyrin unit in dendrimer porphyrin (DP) is surrounded by large poly(benzyl ether) dendritic wedges with ionic peripheries, the resulting electrostatic interaction with oppositely charged polymeric materials has been used to create various functional nano-devices. In this paper, we briefly review DP-based self-assembled biomedical nano-devices, including DP-loaded polyion complex micelles, the ternary complex systems used for gene delivery, polymer-metal complex micelles, the hollow nanocapsules used for combination cancer therapy, and the DP-immobilized surfaces used for diagnostic tools.",

author = "Jeong, {Young Hwan} and Yoon, {Hee Jae} and Jang, {Woo Dong}",

note = "Funding Information: This work was supported by a National Research Foundation (NRF) grant funded by the Korean government (MEST) (no. 2011-0001126). Y.-H. Jeong and H.-J. Yoon acknowledge fellowships from the BK21 program supported by MEST, Korea.",

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AU - Jeong, Young Hwan

AU - Yoon, Hee Jae

AU - Jang, Woo Dong

N1 - Funding Information: This work was supported by a National Research Foundation (NRF) grant funded by the Korean government (MEST) (no. 2011-0001126). Y.-H. Jeong and H.-J. Yoon acknowledge fellowships from the BK21 program supported by MEST, Korea.

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N2 - Dendrimers have attracted great interest for the design of functional materials. Because the core porphyrin unit in dendrimer porphyrin (DP) is surrounded by large poly(benzyl ether) dendritic wedges with ionic peripheries, the resulting electrostatic interaction with oppositely charged polymeric materials has been used to create various functional nano-devices. In this paper, we briefly review DP-based self-assembled biomedical nano-devices, including DP-loaded polyion complex micelles, the ternary complex systems used for gene delivery, polymer-metal complex micelles, the hollow nanocapsules used for combination cancer therapy, and the DP-immobilized surfaces used for diagnostic tools.

AB - Dendrimers have attracted great interest for the design of functional materials. Because the core porphyrin unit in dendrimer porphyrin (DP) is surrounded by large poly(benzyl ether) dendritic wedges with ionic peripheries, the resulting electrostatic interaction with oppositely charged polymeric materials has been used to create various functional nano-devices. In this paper, we briefly review DP-based self-assembled biomedical nano-devices, including DP-loaded polyion complex micelles, the ternary complex systems used for gene delivery, polymer-metal complex micelles, the hollow nanocapsules used for combination cancer therapy, and the DP-immobilized surfaces used for diagnostic tools.

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Dendrimer porphyrin-based self-assembled nano-devices for biomedical applications

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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