TY - GEN
T1 - Decreased macrophage density on carbon nanofiber patterns
AU - Kim, Jong Youl
AU - Khang, Dongwoo
AU - Lee, Jong Eun
AU - Webster, Thomas J.
PY - 2006
Y1 - 2006
N2 - In this study, increased functions of an inflammatory cell (specifically, macrophages) specifically on aligned polycarbonate urethane (PCU) regions rather than on carbon nanofiber (CNFs) regions are described. Specifically, the results showed for the first time that macrophage adhesion and proliferation on aligned CNFs were significantly less than on PCU. The present in vitro study thus provided evidence of the ability of CNFs to down-regulate macrophage adhesion and proliferation important to decrease harmful inflammatory responses, criteria imperative for the future consideration of CNFs for numerous implant applications.
AB - In this study, increased functions of an inflammatory cell (specifically, macrophages) specifically on aligned polycarbonate urethane (PCU) regions rather than on carbon nanofiber (CNFs) regions are described. Specifically, the results showed for the first time that macrophage adhesion and proliferation on aligned CNFs were significantly less than on PCU. The present in vitro study thus provided evidence of the ability of CNFs to down-regulate macrophage adhesion and proliferation important to decrease harmful inflammatory responses, criteria imperative for the future consideration of CNFs for numerous implant applications.
UR - http://www.scopus.com/inward/record.url?scp=40949103628&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40949103628&partnerID=8YFLogxK
U2 - 10.1557/proc-0950-d04-23
DO - 10.1557/proc-0950-d04-23
M3 - Conference contribution
AN - SCOPUS:40949103628
SN - 9781604234060
T3 - Materials Research Society Symposium Proceedings
SP - 155
EP - 161
BT - Materials Research Society Symposium Proceedings
PB - Materials Research Society
T2 - 2006 MRS Fall Meeting
Y2 - 27 November 2006 through 1 December 2006
ER -