TY - JOUR
T1 - Data on optimization of expression and purification of AIMP2-DX2 protein in Escherichia coli
AU - Jha, Roshan
AU - Cho, Hye Young
AU - Mushtaq, Ameeq Ul
AU - Lee, Kiho
AU - Kim, Dae Gyu
AU - Kim, Sunghoon
AU - Jeon, Young Ho
N1 - Publisher Copyright:
© 2017
PY - 2017/4/1
Y1 - 2017/4/1
N2 - AIMP2-DX2 is a splicing variant of AIMP2 protein which has been implicated in human lung cancer and chemoresistance of ovarian cancer (J.W. Choi, D.G. Kim, A.E. Lee, H.R. Kim, J.Y. Lee, N.H. Kwon, et al., 2011; J.W. Choi, J.W. Lee, J.K. Kim, H.K. Jeon, J.J. Choi, D.G. Kim, et al., 2012) [1,2]. We have shown, here, the data for the expression of AIMP2-DX2 protein in Escherichia coli and optimization of the critical steps in purification of AIMP2-DX2. The data described here has been successfully used to get a maximum yield of highly pure AIMP2-DX2 for subsequent characterization of its biophysical property in: “Purification and biophysical characterization of the AIMP2-DX2 protein” (R. Jha, H.Y. Cho, A. Ul Mushtaq, K. Lee, D.G. Kim, S. Kim, et al., 2017) [3].
AB - AIMP2-DX2 is a splicing variant of AIMP2 protein which has been implicated in human lung cancer and chemoresistance of ovarian cancer (J.W. Choi, D.G. Kim, A.E. Lee, H.R. Kim, J.Y. Lee, N.H. Kwon, et al., 2011; J.W. Choi, J.W. Lee, J.K. Kim, H.K. Jeon, J.J. Choi, D.G. Kim, et al., 2012) [1,2]. We have shown, here, the data for the expression of AIMP2-DX2 protein in Escherichia coli and optimization of the critical steps in purification of AIMP2-DX2. The data described here has been successfully used to get a maximum yield of highly pure AIMP2-DX2 for subsequent characterization of its biophysical property in: “Purification and biophysical characterization of the AIMP2-DX2 protein” (R. Jha, H.Y. Cho, A. Ul Mushtaq, K. Lee, D.G. Kim, S. Kim, et al., 2017) [3].
UR - http://www.scopus.com/inward/record.url?scp=85014993256&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85014993256&partnerID=8YFLogxK
U2 - 10.1016/j.dib.2017.03.011
DO - 10.1016/j.dib.2017.03.011
M3 - Article
AN - SCOPUS:85014993256
SN - 2352-3409
VL - 11
SP - 533
EP - 536
JO - Data in Brief
JF - Data in Brief
ER -
