Current status of radical prostatectomy for high-risk prostate cancer

Ho Won Kang, Joo Yong Lee, Jong Kyou Kwon, Seong Uk Jeh, Hae Do Jung, Young Deuk Choi

Research output: Contribution to journalReview articlepeer-review

7 Citations (Scopus)


Despite the wide application of prostate-specific antigen-based screening leading to a profound stage migration in prostate cancer (PC), a significant percentage of men are still being diagnosed with clinically high-risk disease that requires aggressive treatment. Optimal management in these patients remains challenging, and strong advocates for radical prostatectomy (RP), radiotherapy, androgen deprivation therapy, and, increasingly, a multimodal approach abound. Currently, surgery for high-risk PC is frequently applied. RP offers an attractive opportunity for tumor excision either as a definitive management or as a first step in multimodal therapy. Nevertheless, this approach is still controversial. In this review, we discuss the current evidence for the role of RP in this clinical setting, including surgical considerations and outcomes. The role of robot-assisted RP, which is increasingly utilized in Korea in this clinical scenario, is discussed.

Original languageEnglish
Pages (from-to)629-635
Number of pages7
JournalKorean Journal of Urology
Issue number10
Publication statusPublished - 2014 Oct 1

Bibliographical note

Publisher Copyright:
© 2014 The Korean Urological Association.

All Science Journal Classification (ASJC) codes

  • Urology


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