Critical size defect in the canine mandible

Jin Young Huh, Byung Ho Choi, Byung Young Kim, Seoung Ho Lee, Shi Jiang Zhu, Jae Hyung Jung

Research output: Contribution to journalArticlepeer-review

78 Citations (Scopus)


Objective. The purpose of this study was to determine the minimum size defect in a canine mandible that would not spontaneously heal during the dog's natural life (the critical size defect). Study design. Sixteen adult female mongrel dogs underwent continuity resection on both sides of the mandible to create bilateral defects. In 8 dogs, mandibular defects ranging from 5 to 20 mm were created with periosteal resection. In the other 8 dogs, mandibular defects ranging from 30 to 60 mm were created preserving the periosteum. The dogs were then killed at 6 months and the defects examined using radiographs and histologic analysis. Results. When the periosteum was removed, mandibular defects greater than 15 mm failed to heal across the entire defect. However, when the periosteum was preserved, mandibular defects needed to be greater than 50 mm in order to fail to heal. Conclusion. The critical size defect in a canine mandible model is 15 mm when the periosteum is removed and 50 mm when the periosteum is preserved.

Original languageEnglish
Pages (from-to)296-301
Number of pages6
JournalOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Issue number3
Publication statusPublished - 2005 Sept

Bibliographical note

Funding Information:
This work was supported by grant No. R13-2003-13 from the Medical Science and Engineering Research Program of the Korean Science & Engineering Foundation.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology
  • General Dentistry


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