Core/sheath-structured composite nanofibers containing cinnamon oil: Their antibacterial and antifungal properties and acaricidal effect against house dust mites

Yoonwon Jung; Hyukjoo Yang; In Yong Lee; Tai Soon Yong; Seungsin Lee

doi:10.3390/polym12010243

Core/sheath-structured composite nanofibers containing cinnamon oil: Their antibacterial and antifungal properties and acaricidal effect against house dust mites

Yoonwon Jung, Hyukjoo Yang, In Yong Lee, Tai Soon Yong, Seungsin Lee

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory-and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.

Original language	English
Article number	243
Journal	Polymers
Volume	12
Issue number	1
DOIs	https://doi.org/10.3390/polym12010243
Publication status	Published - 2020 Jan 1

Bibliographical note

Funding Information:
Funding: This research was funded by JSPS KAKENHI: 18H05158, 19H02696, 19K15629, 19K22179, 19K21963; JST CREST: JPMJCR19l2; ERCA Japan: 5RF-1802.

Funding Information:
This research was funded by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, project NRF-2016R1D1A1B03930882; and the Brain Korea 21 Plus Project of Dept. of Clothing and Textiles, Yonsei University in 2019.

Funding Information:
Acknowledgments: The authors would appreciate Tatsuo Kojima and Shuichi Hiraoka for their helpful access on mass measurements. This research was supported by financial supports (JSPS Research Fellow, Yazaki Memorial Foundation for Science and Technology, Asahi Glass Foundation, The Amada Foundation, Izumi Science and Technology Foundation, Yashima Environment Technology Foundation, and Iketani Science and Technology Foundation).

Publisher Copyright:
© 2020 by the authors.

All Science Journal Classification (ASJC) codes

Chemistry(all)
Polymers and Plastics

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10.3390/polym12010243

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title = "Core/sheath-structured composite nanofibers containing cinnamon oil: Their antibacterial and antifungal properties and acaricidal effect against house dust mites",

abstract = "This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory-and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.",

author = "Yoonwon Jung and Hyukjoo Yang and Lee, {In Yong} and Yong, {Tai Soon} and Seungsin Lee",

note = "Funding Information: Funding: This research was funded by JSPS KAKENHI: 18H05158, 19H02696, 19K15629, 19K22179, 19K21963; JST CREST: JPMJCR19l2; ERCA Japan: 5RF-1802. Funding Information: This research was funded by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, project NRF-2016R1D1A1B03930882; and the Brain Korea 21 Plus Project of Dept. of Clothing and Textiles, Yonsei University in 2019. Funding Information: Acknowledgments: The authors would appreciate Tatsuo Kojima and Shuichi Hiraoka for their helpful access on mass measurements. This research was supported by financial supports (JSPS Research Fellow, Yazaki Memorial Foundation for Science and Technology, Asahi Glass Foundation, The Amada Foundation, Izumi Science and Technology Foundation, Yashima Environment Technology Foundation, and Iketani Science and Technology Foundation). Publisher Copyright: {\textcopyright} 2020 by the authors.",

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doi = "10.3390/polym12010243",

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AU - Yong, Tai Soon

AU - Lee, Seungsin

N1 - Funding Information: Funding: This research was funded by JSPS KAKENHI: 18H05158, 19H02696, 19K15629, 19K22179, 19K21963; JST CREST: JPMJCR19l2; ERCA Japan: 5RF-1802. Funding Information: This research was funded by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, project NRF-2016R1D1A1B03930882; and the Brain Korea 21 Plus Project of Dept. of Clothing and Textiles, Yonsei University in 2019. Funding Information: Acknowledgments: The authors would appreciate Tatsuo Kojima and Shuichi Hiraoka for their helpful access on mass measurements. This research was supported by financial supports (JSPS Research Fellow, Yazaki Memorial Foundation for Science and Technology, Asahi Glass Foundation, The Amada Foundation, Izumi Science and Technology Foundation, Yashima Environment Technology Foundation, and Iketani Science and Technology Foundation). Publisher Copyright: © 2020 by the authors.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory-and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.

AB - This study aimed to fabricate core/sheath-structured composite nanofibers containing cinnamon oil by emulsion electrospinning and to investigate their acaricidal effect on house dust mites as well as their antibacterial and antifungal properties in relation to cinnamon oil concentration in the nanofibers. An oil-in-water emulsion, which comprised cinnamon oil and poly(vinyl alcohol) solution as oil and water phases, respectively, was used to prepare core/sheath-structured nanofibers. The morphology and the inner structure of the electrospun nanofibers were observed by scanning electron microscopy and confocal laser scanning microscopy. Core/sheath-structured nanofibers containing cinnamon oil were successfully prepared by emulsion electrospinning. The composite nanofibers prepared from an emulsion containing 20 wt% of cinnamon oil exhibited a strong acaricidal effect against house dust mites (Dermatophagoides farinae). The composite nanofibers fabricated from an emulsion containing 4.29 wt% of cinnamon oil showed excellent antimicrobial effects against Staphylococcus aureus and a series of fungi that can trigger respiratory-and skin-related diseases. The release profile of cinnamon oil from the core/sheath-structured nanofibers showed a continuous release of functional ingredients over 28 days. Our findings demonstrate that the use of such fibrous structures could be a promising approach for delivering naturally derived bioactive agents in a controlled way.

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Core/sheath-structured composite nanofibers containing cinnamon oil: Their antibacterial and antifungal properties and acaricidal effect against house dust mites

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