Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity

Ayoung Lee; Young Ju Lee; Hye Jin Yoo; Minkyung Kim; Yeeun Chang; Dong Seog Lee; Jong Ho Lee

doi:10.3390/nu9060558

Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity

Ayoung Lee, Young Ju Lee, Hye Jin Yoo, Minkyung Kim, Yeeun Chang, Dong Seog Lee, Jong Ho Lee

Department of Food and Nutrition

Research output: Contribution to journal › Article › peer-review

85 Citations (Scopus)

Abstract

The aim of this study was to investigate the impact of consuming dairy yogurt containing Lactobacillus paracasei ssp. paracasei (L. paracasei), Bifidobacterium animalis ssp. lactis (B. lactis) and heattreated Lactobacillus plantarum (L. plantarum) on immune function. A randomized, open-label, placebo-controlled study was conducted on 200 nondiabetic subjects. Over a twelve-week period, the test group consumed dairy yogurt containing probiotics each day, whereas the placebo group consumed milk. Natural killer (NK) cell activity, interleukin (IL)-12 and immunoglobulin (Ig) G1 levels were significantly increased in the test group at twelve weeks compared to baseline. Additionally, the test group had significantly greater increases in serum NK cell activity and interferon (IFN)-γ and IgG1 than placebo group. Daily consumption of dairy yogurt containing L. paracasei, B. lactis and heat-treated L. plantarum could be an effective option to improve immune function by enhancing NK cell function and IFN-γ concentration (ClinicalTrials.gov: NCT03051425).

Original language	English
Article number	558
Journal	Nutrients
Volume	9
Issue number	6
DOIs	https://doi.org/10.3390/nu9060558
Publication status	Published - 2017 Jun

Bibliographical note

Publisher Copyright:
© 2017 by the authors. Licensee MDPI, Basel, Switzerland.

All Science Journal Classification (ASJC) codes

Food Science
Nutrition and Dietetics

Access to Document

10.3390/nu9060558

Fingerprint

Dive into the research topics of 'Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity'. Together they form a unique fingerprint.

Cite this

Lee, A., Lee, Y. J., Yoo, H. J., Kim, M., Chang, Y., Lee, D. S., & Lee, J. H. (2017). Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity. Nutrients, 9(6), Article 558. https://doi.org/10.3390/nu9060558

@article{199fa21ca77d492a84caec108cb8e434,

title = "Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity",

abstract = "The aim of this study was to investigate the impact of consuming dairy yogurt containing Lactobacillus paracasei ssp. paracasei (L. paracasei), Bifidobacterium animalis ssp. lactis (B. lactis) and heattreated Lactobacillus plantarum (L. plantarum) on immune function. A randomized, open-label, placebo-controlled study was conducted on 200 nondiabetic subjects. Over a twelve-week period, the test group consumed dairy yogurt containing probiotics each day, whereas the placebo group consumed milk. Natural killer (NK) cell activity, interleukin (IL)-12 and immunoglobulin (Ig) G1 levels were significantly increased in the test group at twelve weeks compared to baseline. Additionally, the test group had significantly greater increases in serum NK cell activity and interferon (IFN)-γ and IgG1 than placebo group. Daily consumption of dairy yogurt containing L. paracasei, B. lactis and heat-treated L. plantarum could be an effective option to improve immune function by enhancing NK cell function and IFN-γ concentration (ClinicalTrials.gov: NCT03051425).",

keywords = "IFN-γ, Immune function, NK cell activity, Probiotics",

author = "Ayoung Lee and Lee, {Young Ju} and Yoo, {Hye Jin} and Minkyung Kim and Yeeun Chang and Lee, {Dong Seog} and Lee, {Jong Ho}",

note = "Publisher Copyright: {\textcopyright} 2017 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2017",

month = jun,

doi = "10.3390/nu9060558",

language = "English",

volume = "9",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "6",

}

Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity. / Lee, Ayoung; Lee, Young Ju; Yoo, Hye Jin et al.
In: Nutrients, Vol. 9, No. 6, 558, 06.2017.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity

AU - Lee, Ayoung

AU - Lee, Young Ju

AU - Yoo, Hye Jin

AU - Kim, Minkyung

AU - Chang, Yeeun

AU - Lee, Dong Seog

AU - Lee, Jong Ho

PY - 2017/6

Y1 - 2017/6

N2 - The aim of this study was to investigate the impact of consuming dairy yogurt containing Lactobacillus paracasei ssp. paracasei (L. paracasei), Bifidobacterium animalis ssp. lactis (B. lactis) and heattreated Lactobacillus plantarum (L. plantarum) on immune function. A randomized, open-label, placebo-controlled study was conducted on 200 nondiabetic subjects. Over a twelve-week period, the test group consumed dairy yogurt containing probiotics each day, whereas the placebo group consumed milk. Natural killer (NK) cell activity, interleukin (IL)-12 and immunoglobulin (Ig) G1 levels were significantly increased in the test group at twelve weeks compared to baseline. Additionally, the test group had significantly greater increases in serum NK cell activity and interferon (IFN)-γ and IgG1 than placebo group. Daily consumption of dairy yogurt containing L. paracasei, B. lactis and heat-treated L. plantarum could be an effective option to improve immune function by enhancing NK cell function and IFN-γ concentration (ClinicalTrials.gov: NCT03051425).

AB - The aim of this study was to investigate the impact of consuming dairy yogurt containing Lactobacillus paracasei ssp. paracasei (L. paracasei), Bifidobacterium animalis ssp. lactis (B. lactis) and heattreated Lactobacillus plantarum (L. plantarum) on immune function. A randomized, open-label, placebo-controlled study was conducted on 200 nondiabetic subjects. Over a twelve-week period, the test group consumed dairy yogurt containing probiotics each day, whereas the placebo group consumed milk. Natural killer (NK) cell activity, interleukin (IL)-12 and immunoglobulin (Ig) G1 levels were significantly increased in the test group at twelve weeks compared to baseline. Additionally, the test group had significantly greater increases in serum NK cell activity and interferon (IFN)-γ and IgG1 than placebo group. Daily consumption of dairy yogurt containing L. paracasei, B. lactis and heat-treated L. plantarum could be an effective option to improve immune function by enhancing NK cell function and IFN-γ concentration (ClinicalTrials.gov: NCT03051425).

KW - IFN-γ

KW - Immune function

KW - NK cell activity

KW - Probiotics

UR - http://www.scopus.com/inward/record.url?scp=85020291803&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85020291803&partnerID=8YFLogxK

U2 - 10.3390/nu9060558

DO - 10.3390/nu9060558

M3 - Article

C2 - 28561762

AN - SCOPUS:85020291803

SN - 2072-6643

VL - 9

JO - Nutrients

JF - Nutrients

IS - 6

M1 - 558

ER -

Consumption of dairy yogurt containing Lactobacillus paracasei ssp. paracasei, Bifidobacterium animalis ssp. lactis and Heat-Treated Lactobacillus plantarum improves immune function including natural killer cell activity

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this