Abstract
A highly efficient asymmetric total synthesis of ent-guadinomic acid [(-)-K01-0509 B] was accomplished from the known epoxy alkenol which is resolved by HKR method. Cross metathesis of the alkene part with acrylate and epoxide opening with azide followed by intramolecular guanidine formation reactions furnished ent-guadinomic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 2949-2952 |
| Number of pages | 4 |
| Journal | Synlett |
| Issue number | 18 |
| DOIs | |
| Publication status | Published - 2009 |
All Science Journal Classification (ASJC) codes
- Organic Chemistry