Comparison of half-time and half-irradiance photodynamic therapy in nonresolving central serous chorioretinopathy

Ji Hwan Lee, Sung Chul Lee, Christopher Seungkyu Lee

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Purpose: To compare the efficacy of half-time and half-irradiance photodynamic therapy (PDT) in patients with nonresolving central serous chorioretinopathy (CSC) Methods: This retrospective study included 32 patients with nonresolving CSC, of whom 14 were treated with half-time PDT and 18 with half-irradiance PDT. Therapeutic outcomes, including central retinal thickness (CRT), subretinal fluid (SRF) height, subfoveal choroidal thickness (SFCT), thickness of the Haller layer (HL), thickness of the choriocapillaris/Sattler layer (SL), and best-corrected visual acuity (BCVA), were measured at baseline, and at 1 and 3 months after treatment. Results: CRT, SRF, and SFCT decreased significantly at 1 and 3 months after treatment in both groups. Thickness of the HL decreased significantly at 1 and 3 months, whereas thickness of the choriocapillaris/SL did not. BCVA demonstrated a significant improvement at 3 months in both groups. Changes in outcome parameters were not significantly different between the 2 groups. Conclusion: Both half-time and half-irradiance PDT were effective in SRF resolution and visual improvement, reducing choroidal thickness mainly on HL.

Original languageEnglish
Pages (from-to)109-115
Number of pages7
JournalJournal of Ocular Pharmacology and Therapeutics
Volume36
Issue number2
DOIs
Publication statusPublished - 2020 Mar

Bibliographical note

Publisher Copyright:
© Copyright 2020, Mary Ann Liebert, Inc., publishers 2020.

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Pharmacology
  • Pharmacology (medical)

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