Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications

Seung Yup Lee; Kyounghwan Na; Julia M. Pakela; James M. Scheiman; Euisik Yoon; Mary Ann Mycek

doi:10.1117/12.2253949

Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications

Seung Yup Lee, Kyounghwan Na, Julia M. Pakela, James M. Scheiman, Euisik Yoon, Mary Ann Mycek

Yonsei Advanced Science Institute

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We present the design, development, and bench-Top verification of an innovative compact clinical system including a miniaturized handheld optoelectronic sensor. The integrated sensor was microfabricated with die-level light-emitting diodes and photodiodes and fits into a 19G hollow needle (internal diameter: 0.75 mm) for optical sensing applications in solid tissues. Bench-Top studies on tissue-simulating phantoms have verified system performance relative to a fiberoptic based tissue spectroscopy system. With dramatically reduced system size and cost, the technology affords spatially configurable designs for optoelectronic light sources and detectors, thereby enabling customized sensing configurations that would be impossible to achieve with needle-based fiber-optic probes.

Original language	English
Title of host publication	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV
Editors	Warren S. Grundfest, Tuan Vo-Dinh, Anita Mahadevan-Jansen
Publisher	SPIE
ISBN (Electronic)	9781510605497
DOIs	https://doi.org/10.1117/12.2253949
Publication status	Published - 2017
Event	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV - San Francisco, United States Duration: 2017 Jan 29 → 2017 Jan 31

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10054
ISSN (Print)	1605-7422

Conference

Conference	Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV
Country/Territory	United States
City	San Francisco
Period	17/1/29 → 17/1/31

Bibliographical note

Publisher Copyright:
© 2017 SPIE.

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2253949

Cite this

Lee, S. Y., Na, K., Pakela, J. M., Scheiman, J. M., Yoon, E., & Mycek, M. A. (2017). Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications. In W. S. Grundfest, T. Vo-Dinh, & A. Mahadevan-Jansen (Eds.), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV [100540Y] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10054). SPIE. https://doi.org/10.1117/12.2253949

Lee, Seung Yup ; Na, Kyounghwan ; Pakela, Julia M. et al. / Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications. Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV. editor / Warren S. Grundfest ; Tuan Vo-Dinh ; Anita Mahadevan-Jansen. SPIE, 2017. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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abstract = "We present the design, development, and bench-Top verification of an innovative compact clinical system including a miniaturized handheld optoelectronic sensor. The integrated sensor was microfabricated with die-level light-emitting diodes and photodiodes and fits into a 19G hollow needle (internal diameter: 0.75 mm) for optical sensing applications in solid tissues. Bench-Top studies on tissue-simulating phantoms have verified system performance relative to a fiberoptic based tissue spectroscopy system. With dramatically reduced system size and cost, the technology affords spatially configurable designs for optoelectronic light sources and detectors, thereby enabling customized sensing configurations that would be impossible to achieve with needle-based fiber-optic probes.",

author = "Lee, {Seung Yup} and Kyounghwan Na and Pakela, {Julia M.} and Scheiman, {James M.} and Euisik Yoon and Mycek, {Mary Ann}",

note = "Publisher Copyright: {\textcopyright} 2017 SPIE.; Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV ; Conference date: 29-01-2017 Through 31-01-2017",

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Lee, SY, Na, K, Pakela, JM, Scheiman, JM, Yoon, E & Mycek, MA 2017, Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications. in WS Grundfest, T Vo-Dinh & A Mahadevan-Jansen (eds), Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV., 100540Y, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10054, SPIE, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, San Francisco, United States, 17/1/29. https://doi.org/10.1117/12.2253949

Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications. / Lee, Seung Yup; Na, Kyounghwan; Pakela, Julia M. et al.
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV. ed. / Warren S. Grundfest; Tuan Vo-Dinh; Anita Mahadevan-Jansen. SPIE, 2017. 100540Y (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10054).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - We present the design, development, and bench-Top verification of an innovative compact clinical system including a miniaturized handheld optoelectronic sensor. The integrated sensor was microfabricated with die-level light-emitting diodes and photodiodes and fits into a 19G hollow needle (internal diameter: 0.75 mm) for optical sensing applications in solid tissues. Bench-Top studies on tissue-simulating phantoms have verified system performance relative to a fiberoptic based tissue spectroscopy system. With dramatically reduced system size and cost, the technology affords spatially configurable designs for optoelectronic light sources and detectors, thereby enabling customized sensing configurations that would be impossible to achieve with needle-based fiber-optic probes.

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Lee SY, Na K, Pakela JM, Scheiman JM, Yoon E, Mycek MA. Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications. In Grundfest WS, Vo-Dinh T, Mahadevan-Jansen A, editors, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV. SPIE. 2017. 100540Y. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2253949

Compact system with handheld microfabricated optoelectronic probe for needle-based tissue sensing applications

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