Clinical outcomes of COVID-19 patients with type 2 diabetes: A population-based study in Korea

Ji Hong You, Sang Ah Lee, Sung Youn Chun, Sun Ok Song, Byung Wan Lee, Dae Jung Kim, Edward J. Boyko

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Background: The aim of this study was to evaluate clinical outcomes in coronavirus disease 2019 (COVID-19) positive patients with type 2 diabetes compared to those without diabetes in Korea. Methods: We extracted claims data for patients diagnosed with COVID-19 from the National Health Insurance Service database in Korea from January 20, 2020 to March 31, 2020. We followed up this cohort until death from COVID-19 or discharge from hospital. Results: A total of 5,473 patients diagnosed with COVID-19 were analyzed, including 495 with type 2 diabetes and 4,978 without diabetes. Patients with type 2 diabetes were more likely to be treated in the intensive care unit (ICU) (P<0.0001). The incidence of in-hospital mortality was higher in patients with type 2 diabetes (P<0.0001). After adjustment for age, sex, insurance status, and comorbidities, odds of ICU admission (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI], 1.02 to 2.49; P=0.0416) and in-hospital mortality (adjusted OR, 1.90; 95% CI, 1.13 to 3.21; P=0.0161) among patients with COVID-19 infection were significantly higher in those with type 2 diabetes. However, there was no significant difference between patients with and without type 2 diabetes in ventilator, oxygen therapy, antibiotics, antiviral drugs, antipyretics, and the incidence of pneumonia after adjustment. Conclusion: COVID-19 positive patients with type 2 diabetes had poorer clinical outcomes with higher risk of ICU admission and in-hospital mortality than those without diabetes. Therefore, medical providers need to consider this more serious clinical course when planning and delivering care to type 2 diabetes patients with COVID-19 infection.

Original languageEnglish
Pages (from-to)901-908
Number of pages8
JournalEndocrinology and Metabolism
Issue number4
Publication statusPublished - 2020 Nov

Bibliographical note

Publisher Copyright:
© 2020 Korean Endocrine Society. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


Dive into the research topics of 'Clinical outcomes of COVID-19 patients with type 2 diabetes: A population-based study in Korea'. Together they form a unique fingerprint.

Cite this