Clinical characteristics and outcomes of juvenile and adult dermatomyositis

Sang Jun Na, Seung Min Kim, Il Nam Sunwoo, Young Chul Choi

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)


Dermatomyositis (DM) is an idiopathic inflammatory myopathy with bimodal onset age distribution. The age of onset is between 5-18 yr in juvenile DM and 45-64 yr in adult DM. DM has a distinct clinical manifestation characterized by proximal muscle weakness, skin rash, extramuscular manifestations (joint contracture, dysphagia, cardiac disturbances, pulmonary symptoms, subcutaneous calcifications), and associated disorders (connective tissue disease, systemic autoimmune diseases, malignancy). The pathogenesis of juvenile and adult DM is presumably similar but there are important differences in some of the clinical manifestations, associated disorders, and outcomes. In this study, we investigated the clinical characteristics and outcomes of 16 patients with juvenile DM and 48 with adult DM. This study recognizes distinctive characteristics of juvenile DM such as higher frequency of neck muscle involvement, subcutaneous calcifications, and better outcomes.

Original languageEnglish
Pages (from-to)715-721
Number of pages7
JournalJournal of Korean medical science
Issue number4
Publication statusPublished - 2009 Aug

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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