Clinical and radiological characteristics of Graves' orbitopathy patients showing spontaneous decompression

Eun Min Kang, Jin Sook Yoon

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Objective To investigate clinical implications and radiological characteristics of spontaneous decompression in patients with Graves' orbitopathy (GO). Methods The medical records and images of GO patients showing spontaneous decompression in computed tomography (CT) scans without any other cause, such as orbital surgery or trauma were retrospectively reviewed. Clinical parameters, including clinical activity score (CAS), modified NOSPECS score, exophthalmometry results, extraocular muscle involvement, and the presence of optic nerve compression were evaluated. Paired orbit analyses of maximum recti muscle diameters, area of lamina papyracea, and number of ethmoid air cell septa were determined quantitatively in the unilaterally decompressed group. Results 77 orbits of 55 patients were found to present spontaneous decompression, which was observed only in the medial orbital wall in all cases. In the paired orbit comparison, maximal diameters of medial (P = 0.009) and lateral recti muscles (P = 0.023) were significantly larger in decompressed orbits than in non-decompressed orbits. However, the incidence of optic neuropathy was not significantly different (P = 0.500). There was no difference in anatomic features of lamina papyracea or ethmoid air cells between decompressed and non-decompressed orbits. Conclusions Spontaneous decompression occurred in the medial wall, associated with enlarged horizontal recti muscles, but not with structures of lamina papyracea or the ethmoidal sinus. Orbital bone remodeling by spontaneous decompression by lowering intraorbital pressure, might have provided a protective effect against the development of optic neuropathy.

Original languageEnglish
Pages (from-to)48-52
Number of pages5
JournalJournal of Cranio-Maxillofacial Surgery
Issue number1
Publication statusPublished - 2015 Jan 1

Bibliographical note

Publisher Copyright:
© 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology


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