Cl3CCONH2/PPh3: A versatile reagent for synthesis of esters

Oraphin Chantarasriwong; Doo Ok Jang; Warinthorn Chavasiri

doi:10.1080/00397910801979361

Cl3CCONH2/PPh3: A versatile reagent for synthesis of esters

Oraphin Chantarasriwong, Doo Ok Jang, Warinthorn Chavasiri

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Cl3CCONH2/PPh3 was a versatile reagent to convert carboxylic acids into their corresponding acid chlorides. This intermediate was clearly confirmed by spectroscopic methods (IR, 1H, 13C NMR). This one-pot reaction of in situ acid chloride generated with various alcohols successfully furnished the corresponding esters in moderate to excellent yields.

Original language	English
Pages (from-to)	2845-2856
Number of pages	12
Journal	Synthetic Communications
Volume	38
Issue number	16
DOIs	https://doi.org/10.1080/00397910801979361
Publication status	Published - 2008 Jan

Bibliographical note

Funding Information:
Financial support from the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program (Grant No. PHD/0223/2548) to O. C. and W. C. is acknowledged. O. C. and W. C. are also indebted to the Graduate School, Chulalongkorn University, for a grant. One of us (D. O. J.) is also grateful for the support from Institute for NanoBio Molecular Assemblies.

All Science Journal Classification (ASJC) codes

Organic Chemistry

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10.1080/00397910801979361

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title = "Cl3CCONH2/PPh3: A versatile reagent for synthesis of esters",

abstract = "Cl3CCONH2/PPh3 was a versatile reagent to convert carboxylic acids into their corresponding acid chlorides. This intermediate was clearly confirmed by spectroscopic methods (IR, 1H, 13C NMR). This one-pot reaction of in situ acid chloride generated with various alcohols successfully furnished the corresponding esters in moderate to excellent yields.",

author = "Oraphin Chantarasriwong and Jang, {Doo Ok} and Warinthorn Chavasiri",

note = "Funding Information: Financial support from the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program (Grant No. PHD/0223/2548) to O. C. and W. C. is acknowledged. O. C. and W. C. are also indebted to the Graduate School, Chulalongkorn University, for a grant. One of us (D. O. J.) is also grateful for the support from Institute for NanoBio Molecular Assemblies.",

year = "2008",

month = jan,

doi = "10.1080/00397910801979361",

language = "English",

volume = "38",

pages = "2845--2856",

journal = "Synthetic Communications",

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publisher = "Taylor and Francis Ltd.",

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T1 - Cl3CCONH2/PPh3

T2 - A versatile reagent for synthesis of esters

AU - Chantarasriwong, Oraphin

AU - Jang, Doo Ok

AU - Chavasiri, Warinthorn

N1 - Funding Information: Financial support from the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program (Grant No. PHD/0223/2548) to O. C. and W. C. is acknowledged. O. C. and W. C. are also indebted to the Graduate School, Chulalongkorn University, for a grant. One of us (D. O. J.) is also grateful for the support from Institute for NanoBio Molecular Assemblies.

PY - 2008/1

Y1 - 2008/1

N2 - Cl3CCONH2/PPh3 was a versatile reagent to convert carboxylic acids into their corresponding acid chlorides. This intermediate was clearly confirmed by spectroscopic methods (IR, 1H, 13C NMR). This one-pot reaction of in situ acid chloride generated with various alcohols successfully furnished the corresponding esters in moderate to excellent yields.

AB - Cl3CCONH2/PPh3 was a versatile reagent to convert carboxylic acids into their corresponding acid chlorides. This intermediate was clearly confirmed by spectroscopic methods (IR, 1H, 13C NMR). This one-pot reaction of in situ acid chloride generated with various alcohols successfully furnished the corresponding esters in moderate to excellent yields.

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ER -

Cl3CCONH2/PPh3: A versatile reagent for synthesis of esters

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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