Cis-2-Aminocyclohex-4-enecarboxylic acid as a new building block of helical foldamers

Sunmi Kwon, Philjae Kang, Moon Gun Choi, Soo Hyuk Choi

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


cis-2-Aminocyclohex-4-enecarboxylic acid (cis-ACHE) is a conformationally constrained β-amino acid. We showed that the conformational preference of a cis-ACHE residue is similar to that of cis-2-aminocyclohexanecarboxylic acid. α/β-Peptides that consist of the alternation of (1S,2R)-cis-ACHE and l-alanine adopted 11/9-helical conformations in solution and in the crystal state.

Original languageEnglish
Pages (from-to)3221-3224
Number of pages4
JournalNew Journal of Chemistry
Issue number5
Publication statusPublished - 2015 May 1

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2015.

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Materials Chemistry


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