TY - JOUR
T1 - Chemical design of nanoparticle probes for high-performance magnetic resonance imaging
AU - Jun, Young Wook
AU - Lee, Jae Hyun
AU - Cheon, Jinwoo
PY - 2008/6/27
Y1 - 2008/6/27
N2 - Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular imaging probes. Herein, we present an overview of recent breakthroughs in the development of new synthetic MNP probes with which the sensitive and target-specific observation of biological events at the molecular and cellular levels is possible.
AB - Synthetic magnetic nanoparticles (MNPs) are emerging as versatile probes in biomedical applications, especially in the area of magnetic resonance imaging (MRI). Their size, which is comparable to biological functional units, and their unique magnetic properties allow their utilization as molecular imaging probes. Herein, we present an overview of recent breakthroughs in the development of new synthetic MNP probes with which the sensitive and target-specific observation of biological events at the molecular and cellular levels is possible.
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U2 - 10.1002/anie.200701674
DO - 10.1002/anie.200701674
M3 - Review article
C2 - 18574805
AN - SCOPUS:48149095263
SN - 1433-7851
VL - 47
SP - 5122
EP - 5135
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 28
ER -