Catastrophic antiphospholipid syndrome in a 7-year-old girl

Jee Min Park, Jae Il Shin, Youn Ho Shin, Dong Soo Kim, Jae Seung Lee, Myung Joon Kim, Seung Koo Lee, Do Yun Lee

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Antiphospholipid syndrome (APS) has been recognized as the leading cause of vascular thrombosis in children. The syndrome may occur in isolation or in association with an underlying systemic disease, particularly systemic lupus erythematosus. Less than 1% of patients with APS present with a life-threatening condition resulting from thrombosis in multiple organs and subsequent multiorgan failure, which is defined as catastrophic APS. Early recognition of APS is essential because prompt and appropriate management can result in favorable outcome. We present the case of a 7-year-old girl with APS who presented with cerebral, femoral, and renal involvement in the second week of the disease progress. The patient presented with multiple thrombotic episodes and rapidly progressive renal failure. Renal cortical infarction was diagnosed by magnetic resonance imaging.

Original languageEnglish
Pages (from-to)1011-1013
Number of pages3
JournalClinical Rheumatology
Issue number6
Publication statusPublished - 2007 Jun

All Science Journal Classification (ASJC) codes

  • Rheumatology


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