Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications

Sung Kyun Ko; Hui Juan Jin; Da Woon Jung; Xizhe Tian; Injae Shin

doi:10.1002/anie.200902370

Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications

Sung Kyun Ko, Hui Juan Jin, Da Woon Jung, Xizhe Tian, Injae Shin

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A change of heart: Cardiosulfa, a small molecule that induces heart deformation during zebrafish development, has been identified by using a forward chemicalgenetic approach. Zebrafish embryos exposed to cardiosulfa have a narrow and elongated heart within an enlarged pericardial sac (see picture; heart marked with green fluorescent protein).

Original language	English
Pages (from-to)	7809-7812
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	42
DOIs	https://doi.org/10.1002/anie.200902370
Publication status	Published - 2009 Oct 5

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)

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10.1002/anie.200902370

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abstract = "A change of heart: Cardiosulfa, a small molecule that induces heart deformation during zebrafish development, has been identified by using a forward chemicalgenetic approach. Zebrafish embryos exposed to cardiosulfa have a narrow and elongated heart within an enlarged pericardial sac (see picture; heart marked with green fluorescent protein).",

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AU - Tian, Xizhe

AU - Shin, Injae

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Cardiosulfa, a small molecule that induces abnormal heart development in zebrafish, and its biological implications

Abstract

All Science Journal Classification (ASJC) codes

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