Cardiac 123I-MIBG scintigraphy in patients with essential tremor

Phil Hyu Lee, Ji Woo Kim, Oh Young Bang, In Soo Joo, Seok Nam Yoon, Kyoon Huh

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


In some cases, it is difficult to differentiate essential tremor (ET) from Parkinson's disease (PD), especially in the early stages of the disease. We investigated cardiac sympathetic dysfunction using 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 22 patients with ET, in comparison with early PD and tremor-dominant PD (TDPD). The mean ratio of 123I-MIBG uptake in the region of interest in the heart to that in the mediastinum (H/M ratio) was significantly greater in patients with ET (1.99 ± 0.21) than in those with either TDPD (1.28 ± 0.11) or early PD (1.28 ± 0.17; each P < 0.001). The H/M ratio in all patients with ET was greater than two standard deviations above the range of the ratio in the patients with early PD or TDPD.

Original languageEnglish
Pages (from-to)1235-1238
Number of pages4
JournalMovement Disorders
Issue number8
Publication statusPublished - 2006 Aug

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology


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