Cardiac 123I-MIBG scintigraphy in patients with drug induced parkinsonism

Phil Hyu Lee; J. S. Kim; D. H. Shin; S. N. Yoon; K. Huh

doi:10.1136/jnnp.2005.073999

Cardiac ¹²³I-MIBG scintigraphy in patients with drug induced parkinsonism

Phil Hyu Lee, J. S. Kim, D. H. Shin, S. N. Yoon, K. Huh

Department of Neurology

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

Cardiac sympathetic dysfunction was investigated using ¹²³I- metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson's disease (mean (SD): 2.07 (0.39) v 1.28 (0.15), p<0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and responded dramatically to levodopa.

Original language	English
Pages (from-to)	372-374
Number of pages	3
Journal	Journal of Neurology, Neurosurgery and Psychiatry
Volume	77
Issue number	3
DOIs	https://doi.org/10.1136/jnnp.2005.073999
Publication status	Published - 2006 Mar

All Science Journal Classification (ASJC) codes

Surgery
Clinical Neurology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/jnnp.2005.073999

Cite this

@article{a358c0d6f83245d8b628232192c5595b,

title = "Cardiac 123I-MIBG scintigraphy in patients with drug induced parkinsonism",

abstract = "Cardiac sympathetic dysfunction was investigated using 123I- metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson's disease (mean (SD): 2.07 (0.39) v 1.28 (0.15), p<0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and responded dramatically to levodopa.",

author = "Lee, {Phil Hyu} and Kim, {J. S.} and Shin, {D. H.} and Yoon, {S. N.} and K. Huh",

year = "2006",

month = mar,

doi = "10.1136/jnnp.2005.073999",

language = "English",

volume = "77",

pages = "372--374",

journal = "Journal of Neurology, Neurosurgery and Psychiatry",

issn = "0022-3050",

publisher = "BMJ Publishing Group",

number = "3",

}

TY - JOUR

T1 - Cardiac 123I-MIBG scintigraphy in patients with drug induced parkinsonism

AU - Lee, Phil Hyu

AU - Kim, J. S.

AU - Shin, D. H.

AU - Yoon, S. N.

AU - Huh, K.

PY - 2006/3

Y1 - 2006/3

N2 - Cardiac sympathetic dysfunction was investigated using 123I- metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson's disease (mean (SD): 2.07 (0.39) v 1.28 (0.15), p<0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and responded dramatically to levodopa.

AB - Cardiac sympathetic dysfunction was investigated using 123I- metaiodobenzylguanidine (MIBG) myocardial scintigraphy in 20 patients with drug induced parkinsonism (DIP). The mean heart to mediastinum ratio was significantly greater in patients with DIP than in those with Parkinson's disease (mean (SD): 2.07 (0.39) v 1.28 (0.15), p<0.001). MIBG uptake was not different between the DIP patients and controls. Two DIP patients whose MIBG uptake was significantly reduced showed persistent parkinsonism and responded dramatically to levodopa.

UR - http://www.scopus.com/inward/record.url?scp=33644553116&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644553116&partnerID=8YFLogxK

U2 - 10.1136/jnnp.2005.073999

DO - 10.1136/jnnp.2005.073999

M3 - Article

C2 - 16103041

AN - SCOPUS:33644553116

SN - 0022-3050

VL - 77

SP - 372

EP - 374

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

IS - 3

ER -