Calcium phosphate nano-composite with bone morphogenetic protein

M. Park; H. Kim; J. W. Lee; K. Y. Lee; H. M. Kim; S. H. Moon; H. M. Lee

doi:10.4028/0-87849-422-7.361

Calcium phosphate nano-composite with bone morphogenetic protein

M. Park, H. Kim, J. W. Lee, K. Y. Lee, H. M. Kim, S. H. Moon, H. M. Lee

Department of Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

Abstract

Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.

Original language	English
Pages (from-to)	361-364
Number of pages	4
Journal	Key Engineering Materials
Volume	330-332 I
DOIs	https://doi.org/10.4028/0-87849-422-7.361
Publication status	Published - 2007

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

Access to Document

10.4028/0-87849-422-7.361

Cite this

@article{b2d31f1c3c9f49f7ba3f984659ced9a4,

title = "Calcium phosphate nano-composite with bone morphogenetic protein",

abstract = "Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.",

author = "M. Park and H. Kim and Lee, {J. W.} and Lee, {K. Y.} and Kim, {H. M.} and Moon, {S. H.} and Lee, {H. M.}",

year = "2007",

doi = "10.4028/0-87849-422-7.361",

language = "English",

volume = "330-332 I",

pages = "361--364",

journal = "Key Engineering Materials",

issn = "1013-9826",

publisher = "Trans Tech Publications",

}

TY - JOUR

T1 - Calcium phosphate nano-composite with bone morphogenetic protein

AU - Park, M.

AU - Kim, H.

AU - Lee, J. W.

AU - Lee, K. Y.

AU - Kim, H. M.

AU - Moon, S. H.

AU - Lee, H. M.

PY - 2007

Y1 - 2007

N2 - Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.

AB - Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.

UR - http://www.scopus.com/inward/record.url?scp=33846320808&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846320808&partnerID=8YFLogxK

U2 - 10.4028/0-87849-422-7.361

DO - 10.4028/0-87849-422-7.361

M3 - Article

AN - SCOPUS:33846320808

SN - 1013-9826

VL - 330-332 I

SP - 361

EP - 364

JO - Key Engineering Materials

JF - Key Engineering Materials

ER -

Calcium phosphate nano-composite with bone morphogenetic protein

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this