TY - GEN
T1 - Biomechanical tests of osteoporotic vertebral trabecular bone using finite element analysis based on micro-CT
AU - Woo, Dae Gon
AU - Lee, Tae Woo
AU - Ko, Chang Yong
AU - Kim, Han Sung
AU - Won, Ye Yeon
PY - 2006
Y1 - 2006
N2 - Osteoporosis results in high fracture risks of vertebral bone. A considerable amount of work has been done to investigate the biomechanical characteristics of osteoporotic vertebral trabecular bone. Previous researchers studied the elastic characteristics using a micro-finite element (micro-FE) model, used to analyze realistic trabecular architectures in full detail, based on micro-computed tomography (μCT). Since osteoporotic compression fracture is closely associated with the mechanical characteristics of the vertebral trabecular bone and there were few micro-FE models to account for all of the elastic and plastic characteristics in vertebral trabecular bone, this study analyzed the effect of voxel resolution on the plastic as well as the elastic characteristics of three-dimensional (3D) osteoporotic lumbar trabecular bone models. Also, we evaluated the effect of specimen size on this problem. It has been reported that a cubic specimen with side length 6.5mm was suggested as standard specimens for the experimental test of trabecular bone. Current study examined whether or not the effect of the specimen geometry on the experimental test may be also applied to the simulated compression test of trabecular bone specimens. The experimental test employing the rapid prototyping (RP) technique and INSTRON test machine is performed to indirectly validate the results of the simulated compression test by micro-FE analysis. The review finished with the verification about the effects of the simulated compression test.
AB - Osteoporosis results in high fracture risks of vertebral bone. A considerable amount of work has been done to investigate the biomechanical characteristics of osteoporotic vertebral trabecular bone. Previous researchers studied the elastic characteristics using a micro-finite element (micro-FE) model, used to analyze realistic trabecular architectures in full detail, based on micro-computed tomography (μCT). Since osteoporotic compression fracture is closely associated with the mechanical characteristics of the vertebral trabecular bone and there were few micro-FE models to account for all of the elastic and plastic characteristics in vertebral trabecular bone, this study analyzed the effect of voxel resolution on the plastic as well as the elastic characteristics of three-dimensional (3D) osteoporotic lumbar trabecular bone models. Also, we evaluated the effect of specimen size on this problem. It has been reported that a cubic specimen with side length 6.5mm was suggested as standard specimens for the experimental test of trabecular bone. Current study examined whether or not the effect of the specimen geometry on the experimental test may be also applied to the simulated compression test of trabecular bone specimens. The experimental test employing the rapid prototyping (RP) technique and INSTRON test machine is performed to indirectly validate the results of the simulated compression test by micro-FE analysis. The review finished with the verification about the effects of the simulated compression test.
UR - http://www.scopus.com/inward/record.url?scp=46249105562&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=46249105562&partnerID=8YFLogxK
U2 - 10.1109/ICBPE.2006.348590
DO - 10.1109/ICBPE.2006.348590
M3 - Conference contribution
AN - SCOPUS:46249105562
SN - 8190426249
SN - 9788190426244
T3 - ICBPE 2006 - Proceedings of the 2006 International Conference on Biomedical and Pharmaceutical Engineering
SP - 231
EP - 236
BT - ICBPE 2006 - Proceedings of the 2006 International Conference on Biomedical and Pharmaceutical Engineering
T2 - ICBPE 2006 - 2006 International Conference on Biomedical and Pharmaceutical Engineering
Y2 - 11 December 2006 through 14 December 2006
ER -