TY - JOUR
T1 - Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea
AU - Lee, Kyungwon
AU - Yum, Jong Hwa
AU - Yong, Dongeun
AU - Jeong, Seok Hoon
AU - Rossolini, Gian Maria
AU - Docquier, Jean Denis
AU - Chong, Yunsop
PY - 2011/12
Y1 - 2011/12
N2 - The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.
AB - The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.
UR - http://www.scopus.com/inward/record.url?scp=81555211915&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=81555211915&partnerID=8YFLogxK
U2 - 10.1128/AAC.05341-11
DO - 10.1128/AAC.05341-11
M3 - Article
C2 - 21911565
AN - SCOPUS:81555211915
SN - 0066-4804
VL - 55
SP - 5930
EP - 5932
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 12
ER -
