Although tissue engineering using human-induced pluripotent stem cells is a promising approach for treatment of cardiovascular diseases, some limiting factors include the survival, electrical integration, maturity, scalability, and immune response of three-dimensional (3D) engineered tissues. Here we discuss these important roadblocks facing the tissue engineering field and suggest potential approaches to overcome these challenges.
Bibliographical notePublisher Copyright:
© 2018, This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
All Science Journal Classification (ASJC) codes
- Medicine (miscellaneous)
- General Biochemistry,Genetics and Molecular Biology
- General Agricultural and Biological Sciences