Bifidogenic effect of glucooligosaccharide prepared from glucose by extrusion process

Jun Bae Ahn, Jae Kwan Hwang, Chong Tai Kim, K. E.H.O. Lee, Jong Hyun Park

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


In order to investigate effect of glucooligosaccharide (GOS) prepared by extrusion process as a bifidogenic factor, cultivation of Bifidobacterium sp., Bacteroides fragilis and Clostridium perfringens was done and analyzed. B. fragilis and C. perfringens were able to utilize only 16% and 11% of the oligosaccharides in GOS, respectively, whilst Bifidobacterium sp. FBD-22 could utilize 38%. Especially, many kinds of oligosaccharides in GOS were able to be utilized selectively only by Bifidobacterium spin case that GOS, as a carbon source, was used in the co-cultivation by Bifidobacterium sp., B. fragilis and C. perfringens, growth of Bifidobacterium sp. was not influenced by the existence of B. fragilis and C. perfringens. Bifidobacterium sp. showed advantage on carbon source competition for GOS with B. fragilis. Acetic acid, antimicrobial agent in the intestine, was produced two times more from GOS than glucose in co-cultures of three strains. Therefore, it is suggested that GOS can be a potent bifidogenic factor which proliferates the population of Bifidobacterium sp. and may finally improve the intestinal environments of human.

Original languageEnglish
Pages (from-to)174-179
Number of pages6
JournalJournal of microbiology and biotechnology
Issue number3
Publication statusPublished - 1997

Bibliographical note

Funding Information:
Financial support.  This work was supported by Gilead Sciences.

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology


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