Benzimidazole and thiourea conjugated fluorescent hybrid receptor for selective recognition of PO43 -

Gang Woo Lee; Narinder Singh; Doo Ok Jang

doi:10.1016/j.tetlet.2008.01.107

Benzimidazole and thiourea conjugated fluorescent hybrid receptor for selective recognition of PO₄^{3 -}

Gang Woo Lee, Narinder Singh, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

We synthesized a novel hybrid receptor bearing an array of hydrogen bond donors from benzimidazole and thiourea moieties. The recognition behavior of the receptor toward various anions has been evaluated in a DMSO/H₂O (8:2, v/v) solvent system. The receptor showed changes in fluorescent intensity only with PO₄^{3 -}, and it showed no such significant response to any of the other anions such as F^-, Cl^-, Br^-, I^-, CN^-, ClO₄^-, H₂ PO₄^-, HPO₄^{2 -}, AcO^-, NO₂^-, CO₃^{2 -}, HCO₃^-, SO₄^{2 -}, and HSO₄^-. The receptor is highly selective in recognizing PO₄^{3 -}even in the presence of other anions in aqueous DMSO.

Original language	English
Pages (from-to)	1952-1956
Number of pages	5
Journal	Tetrahedron Letters
Volume	49
Issue number	12
DOIs	https://doi.org/10.1016/j.tetlet.2008.01.107
Publication status	Published - 2008 Mar 17

Bibliographical note

Funding Information:
This work was supported by the Center for Bioactive Molecular Hybrids at Yonsei University.

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2008.01.107

Cite this

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title = "Benzimidazole and thiourea conjugated fluorescent hybrid receptor for selective recognition of PO43 -",

abstract = "We synthesized a novel hybrid receptor bearing an array of hydrogen bond donors from benzimidazole and thiourea moieties. The recognition behavior of the receptor toward various anions has been evaluated in a DMSO/H2O (8:2, v/v) solvent system. The receptor showed changes in fluorescent intensity only with PO43 -, and it showed no such significant response to any of the other anions such as F-, Cl-, Br-, I-, CN-, ClO4-, H2 PO4-, HPO42 -, AcO-, NO2-, CO32 -, HCO3-, SO42 -, and HSO4-. The receptor is highly selective in recognizing PO43 -even in the presence of other anions in aqueous DMSO.",

author = "Lee, {Gang Woo} and Narinder Singh and Jang, {Doo Ok}",

note = "Funding Information: This work was supported by the Center for Bioactive Molecular Hybrids at Yonsei University. ",

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T1 - Benzimidazole and thiourea conjugated fluorescent hybrid receptor for selective recognition of PO43 -

AU - Lee, Gang Woo

AU - Singh, Narinder

AU - Jang, Doo Ok

N1 - Funding Information: This work was supported by the Center for Bioactive Molecular Hybrids at Yonsei University.

PY - 2008/3/17

Y1 - 2008/3/17

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AB - We synthesized a novel hybrid receptor bearing an array of hydrogen bond donors from benzimidazole and thiourea moieties. The recognition behavior of the receptor toward various anions has been evaluated in a DMSO/H2O (8:2, v/v) solvent system. The receptor showed changes in fluorescent intensity only with PO43 -, and it showed no such significant response to any of the other anions such as F-, Cl-, Br-, I-, CN-, ClO4-, H2 PO4-, HPO42 -, AcO-, NO2-, CO32 -, HCO3-, SO42 -, and HSO4-. The receptor is highly selective in recognizing PO43 -even in the presence of other anions in aqueous DMSO.

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